ID   Jurkat-111
AC   CVCL_U326
SY   Jurkat 111; J-111
DR   ATCC; CRL-8129
DR   BioSample; SAMN03471193
DR   cancercelllines; CVCL_U326
DR   Wikidata; Q54899146
RX   Patent=EP0142268A1;
RX   Patent=US5795777;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8129.
CC   Population: Caucasian.
CC   Characteristics: Highly increased IL2 expression.
CC   Sequence variation: Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCIt; C17262; X-Ray.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): ATCC
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 8,10,11
ST   D16S539: 11,12
ST   D5S818: 9
ST   D7S820: 8,10,11
ST   TH01: 6,9.3
ST   TPOX: 8,10
ST   vWA: 18,19
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0065 ! Jurkat
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 21
//
RX   Patent=EP0142268A1;
RA   Taniguchi T., Matsui H., Hamuro J., Sato T., Sano K.;
RT   "Saccharomyces cerevisiae possessing gene coding for interleukin-2
RT   polypeptide and method for producing interleukin-2 using the yeast.";
RL   Patent number EP0142268A1, 22-May-1985.
//
RX   Patent=US5795777;
RA   Taniguchi T., Muramatsu M., Sugano H., Matsui H., Kashima N.,
RA   Hamuro J.;
RT   "Gene coded for interleukin-2 polypeptide, recombinant DNA carrying
RT   the said gene, a living cell line possessing the recombinant DNA, and
RT   method for producing interleukin-2 using the said cell.";
RL   Patent number US5795777, 18-Aug-1998.
//