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Cellosaurus AG09908 (CVCL_T872)

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Cell line name AG09908
Synonyms AG09908*A
Accession CVCL_T872
Resource Identification Initiative To cite this cell line use: AG09908 (RRID:CVCL_T872)
Comments Population: Caucasian; German.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:9509; PSEN2; Simple; p.Asn141Ile (c.422A>T); ClinVar=VCV000008845; Zygosity=Heterozygous (PubMed=10408806; Coriell=AG09908).
Disease Alzheimer's disease 4 (NCIt: C123413)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_LE08 (AG25370)CVCL_YX93 (CS08iFAD-nxx)CVCL_ZZ65 (HUi001-A)
CVCL_A4PF (MUNIi007-A)CVCL_T875 (PS2-1)CVCL_T876 (PS2-2)
CVCL_C0CV (PSEN2-N141I-hiPSC)
Sex of cell Female
Age at sampling 81Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=10408806; DOI=10.1006/nbdi.1999.0236
Lisa N. Geller, Huntington Potter;
Chromosome missegregation and trisomy 21 mosaicism in Alzheimer's disease.
Neurobiol. Dis. 6:167-179(1999)

PubMed=21900357; DOI=10.1093/hmg/ddr394
Takuya Yagi, Daisuke Ito, Yohei Okada, Wado Akamatsu, Yoshihiro Nihei, Takahito Yoshizaki, Shinya Yamanaka, Hideyuki Okano, Norihiro Suzuki;
Modeling familial Alzheimer's disease with induced pluripotent stem cells.
Hum. Mol. Genet. 20:4530-4539(2011)

Cross-references
Cell line collections (Providers) Coriell; AG09908
Cell line databases/resources CLO; CLO_0021929
Encyclopedic resources Wikidata; Q54743097
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number18