Cellosaurus cell line MUNIi007-A (CVCL

Cross-references
Cell line name	MUNIi007-A
Synonyms	ADF81; fAD3
Accession	CVCL_A4PF
Resource Identification Initiative	To cite this cell line use: MUNIi007-A (RRID:CVCL_A4PF)
Comments	From: Masaryk University; Brno; Czech Republic. Population: Caucasian; German. Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:9509; PSEN2; Simple; p.Asn141Ile (c.422A>T); ClinVar=VCV000008845; Zygosity=Heterozygous (PubMed=34088008).
Disease	Alzheimer's disease 4 (NCIt: C123413) Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_T872 (AG09908)
Sex of cell	Female
Age at sampling	81Y
Category	Induced pluripotent stem cell
Publications	PubMed=34088008; DOI=10.1016/j.scr.2021.102379 Jan Raska, Hana Hribkova, Hana Klimova, Veronika Fedorova, Martin Barak, Thomas Barta, Veronika Pospisilova, Simona Vochyanova, Tereza Vanova, Dasa Bohaciakova; Generation of six human iPSC lines from patients with a familial Alzheimer's disease (n = 3) and sex- and age-matched healthy controls (n = 3). Stem Cell Res. 53:102379-102379(2021)
Cell line databases/resources	hPSCreg; MUNIi007-A
Biological sample resources	BioSamples; SAMEA7873289
Encyclopedic resources	Wikidata; Q105510228
Entry history
Entry creation	12-Jan-2021
Last entry update	19-Dec-2024
Version number	7