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Cellosaurus PS2-1 (CVCL_T875)

[Text version]
Cell line name PS2-1
Accession CVCL_T875
Resource Identification Initiative To cite this cell line use: PS2-1 (RRID:CVCL_T875)
Comments Population: Caucasian; German.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 9509; PSEN2; Simple; p.Asn141Ile (c.422A>T); ClinVar=VCV000008845; Zygosity=Heterozygous (PubMed=21900357).
Disease Alzheimer's disease 4 (NCIt: C123413)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_T872 (AG09908)
Sex of cell Female
Age at sampling 81Y
Category Induced pluripotent stem cell
Publications

PubMed=21900357; DOI=10.1093/hmg/ddr394
Yagi T., Ito D., Okada Y., Akamatsu W., Nihei Y., Yoshizaki T., Yamanaka S., Okano H., Suzuki N.
Modeling familial Alzheimer's disease with induced pluripotent stem cells.
Hum. Mol. Genet. 20:4530-4539(2011)

Cross-references
Cell line databases/resources SKIP; SKIP000196
SKIP; SKIP001015
Encyclopedic resources Wikidata; Q54948413
Gene expression databases GEO; GSM701544
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number15