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Cellosaurus RB355 (CVCL_S611)

[Text version]
Cell line name RB355
Synonyms RB 355; RB-355
Accession CVCL_S611
Resource Identification Initiative To cite this cell line use: RB355 (RRID:CVCL_S611)
Comments Problematic cell line: Contaminated. Shown to be a Y-79 derivative (PubMed=1679230). Originally thought to originate from a male patient with retinoblastoma.
Population: Caucasian.
Doubling time: 81.4 +- 5.7 hours (PubMed=2751270); 66 hours (PubMed=25326674).
Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1893 (Y-79)
Children:
CVCL_B7IH (RB355 CDDP-R)CVCL_B7II (RB355 Eto-R)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line
Publications

PubMed=4018796; DOI=10.1007/BF00295364
Jeremy Andrew Squire, Brenda Louise Gallie, Robert A. Phillips;
A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma.
Hum. Genet. 70:291-301(1985)

PubMed=2751270
Helen S.L. Chan, Marc D. Canton, Brenda Louise Gallie;
Chemosensitivity and multidrug resistance to antineoplastic drugs in retinoblastoma cell lines.
Anticancer Res. 9:469-474(1989)

PubMed=2917337; DOI=10.1016/0165-4608(89)90079-4
Bernhard Horsthemke, Valerie Greger, Reinhard Becher, Eberhard Passarge;
Mechanism of i(6p) formation in retinoblastoma tumor cells.
Cancer Genet. Cytogenet. 37:95-102(1989)

PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x
Sabine Griegel, Kerstin Heise, Andrea Kindler-Rohrborn, Manfred Fedor Rajewsky;
In vitro differentiation of human retinoblastoma cells into neuronal phenotypes.
Differentiation 45:250-257(1990)

PubMed=2365495; DOI=10.1002/ijc.2910460123
Sabine Griegel, Chen Hong, Roland Frotschl, Dieter F. Hulser, Valerie Greger, Bernhard Horsthemke, Manfred Fedor Rajewsky;
Newly established human retinoblastoma cell lines exhibit an 'immortalized' but not an invasive phenotype in vitro.
Int. J. Cancer 46:125-132(1990)

PubMed=1679230; DOI=10.3109/13816819109023085
Steven A. Madreperla, Robert Bookstein, Oliver W. Jones, Wen-Hwa Lee;
Retinoblastoma cell lines Y79, RB355 and WERI-Rb27 are genetically related.
Ophthalmic Paediatr. Genet. 12:49-56(1991)

PubMed=1682862; DOI=10.1016/S0161-6420(91)32134-1
Helen S.L. Chan, Paul Scott Thorner, George Haddad, Brenda Louise Gallie;
Multidrug-resistant phenotype in retinoblastoma correlates with P-glycoprotein expression.
Ophthalmology 98:1425-1431(1991)

PubMed=23498719; DOI=10.1016/S1470-2045(13)70045-7
Diane E. Rushlow, Berber M. Mol, Jennifer Y. Kennett, Stephanie Yee, Sanja Pajovic, Brigitte L. Theriault, Nadia L. Prigoda-Lee, Clarellen Spencer, Helen Dimaras, Timothy W. Corson, Renee Pang ...Show all 25 authors... , Christine Massey, Roseline Godbout, Zhe Jiang, Eldad Zacksenhaus, Katherine Paton, Annette C. Moll, Claude Houdayer, Anthony Raizis, William Halliday, Wan L. Lam, Paul Christopher Boutros, Dietmar R. Lohmann, Josephine C. Dorsman, Brenda Louise Gallie; Show fewer authors
Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies.
Lancet Oncol. 14:327-334(2013)

PubMed=25326674; DOI=10.1007/s00418-014-1285-z
Maike Anna Busch, Claudia Philippeit, Andreas Weise, Nicole Dunker;
Re-characterization of established human retinoblastoma cell lines.
Histochem. Cell Biol. 143:325-338(2015)

PubMed=29192327; DOI=10.3892/or.2017.6100; PMCID=PMC5783599
Maike Anna Busch, David Papior, Harald Stephan, Nicole Dunker;
Characterization of etoposide- and cisplatin-chemoresistant retinoblastoma cell lines.
Oncol. Rep. 39:160-172(2018)

PubMed=30584916; DOI=10.1016/j.yexcr.2018.12.018
Melanie Schwermer, Michaela Hiber, Sabine Dreesmann, Anja Rieb, Jessica Theissen, Thomas Herold, Alexander Schramm, Petra Temming, Laura Steenpass;
Comprehensive characterization of RB1 mutant and MYCN amplified retinoblastoma cell lines.
Exp. Cell Res. 375:92-99(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S611
Encyclopedic resources Wikidata; Q54949306
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number20