ID   RB355
AC   CVCL_S611
SY   RB 355; RB-355
DR   cancercelllines; CVCL_S611
DR   Wikidata; Q54949306
RX   PubMed=1679230;
RX   PubMed=1682862;
RX   PubMed=2090524;
RX   PubMed=2365495;
RX   PubMed=2751270;
RX   PubMed=2917337;
RX   PubMed=4018796;
RX   PubMed=23498719;
RX   PubMed=25326674;
RX   PubMed=29192327;
RX   PubMed=30584916;
CC   Problematic cell line: Contaminated. Shown to be a Y-79 derivative (PubMed=1679230). Originally thought to originate from a male patient with retinoblastoma.
CC   Population: Caucasian.
CC   Doubling time: 81.4 +- 5.7 hours (PubMed=2751270); 66 hours (PubMed=25326674).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
DI   NCIt; C7541; Retinoblastoma
DI   ORDO; Orphanet_790; Retinoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1893 ! Y-79
SX   Female
AG   2Y6M
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 19-12-24; Version: 20
//
RX   PubMed=1679230; DOI=10.3109/13816819109023085;
RA   Madreperla, Steven A.
RA   Bookstein, Robert
RA   Jones, Oliver W.
RA   Lee, Wen-Hwa
RT   "Retinoblastoma cell lines Y79, RB355 and WERI-Rb27 are genetically
RT   related.";
RL   Ophthalmic Paediatr. Genet. 12:49-56(1991).
//
RX   PubMed=1682862; DOI=10.1016/S0161-6420(91)32134-1;
RA   Chan, Helen S.L.
RA   Thorner, Paul Scott
RA   Haddad, George
RA   Gallie, Brenda Louise
RT   "Multidrug-resistant phenotype in retinoblastoma correlates with
RT   P-glycoprotein expression.";
RL   Ophthalmology 98:1425-1431(1991).
//
RX   PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x;
RA   Griegel, Sabine
RA   Heise, Kerstin
RA   Kindler-Rohrborn, Andrea
RA   Rajewsky, Manfred Fedor
RT   "In vitro differentiation of human retinoblastoma cells into neuronal
RT   phenotypes.";
RL   Differentiation 45:250-257(1990).
//
RX   PubMed=2365495; DOI=10.1002/ijc.2910460123;
RA   Griegel, Sabine
RA   Hong, Chen
RA   Frotschl, Roland
RA   Hulser, Dieter F.
RA   Greger, Valerie
RA   Horsthemke, Bernhard
RA   Rajewsky, Manfred Fedor
RT   "Newly established human retinoblastoma cell lines exhibit an
RT   'immortalized' but not an invasive phenotype in vitro.";
RL   Int. J. Cancer 46:125-132(1990).
//
RX   PubMed=2751270;
RA   Chan, Helen S.L.
RA   Canton, Marc D.
RA   Gallie, Brenda Louise
RT   "Chemosensitivity and multidrug resistance to antineoplastic drugs in
RT   retinoblastoma cell lines.";
RL   Anticancer Res. 9:469-474(1989).
//
RX   PubMed=2917337; DOI=10.1016/0165-4608(89)90079-4;
RA   Horsthemke, Bernhard
RA   Greger, Valerie
RA   Becher, Reinhard
RA   Passarge, Eberhard
RT   "Mechanism of i(6p) formation in retinoblastoma tumor cells.";
RL   Cancer Genet. Cytogenet. 37:95-102(1989).
//
RX   PubMed=4018796; DOI=10.1007/BF00295364;
RA   Squire, Jeremy Andrew
RA   Gallie, Brenda Louise
RA   Phillips, Robert A.
RT   "A detailed analysis of chromosomal changes in heritable and
RT   non-heritable retinoblastoma.";
RL   Hum. Genet. 70:291-301(1985).
//
RX   PubMed=23498719; DOI=10.1016/S1470-2045(13)70045-7;
RA   Rushlow, Diane E.
RA   Mol, Berber M.
RA   Kennett, Jennifer Y.
RA   Yee, Stephanie
RA   Pajovic, Sanja
RA   Theriault, Brigitte L.
RA   Prigoda-Lee, Nadia L.
RA   Spencer, Clarellen
RA   Dimaras, Helen
RA   Corson, Timothy W.
RA   Pang, Renee
RA   Massey, Christine
RA   Godbout, Roseline
RA   Jiang, Zhe
RA   Zacksenhaus, Eldad
RA   Paton, Katherine
RA   Moll, Annette C.
RA   Houdayer, Claude
RA   Raizis, Anthony
RA   Halliday, William
RA   Lam, Wan L.
RA   Boutros, Paul Christopher
RA   Lohmann, Dietmar R.
RA   Dorsman, Josephine C.
RA   Gallie, Brenda Louise
RT   "Characterisation of retinoblastomas without RB1 mutations: genomic,
RT   gene expression, and clinical studies.";
RL   Lancet Oncol. 14:327-334(2013).
//
RX   PubMed=25326674; DOI=10.1007/s00418-014-1285-z;
RA   Busch, Maike Anna
RA   Philippeit, Claudia
RA   Weise, Andreas
RA   Dunker, Nicole
RT   "Re-characterization of established human retinoblastoma cell lines.";
RL   Histochem. Cell Biol. 143:325-338(2015).
//
RX   PubMed=29192327; DOI=10.3892/or.2017.6100; PMCID=PMC5783599;
RA   Busch, Maike Anna
RA   Papior, David
RA   Stephan, Harald
RA   Dunker, Nicole
RT   "Characterization of etoposide- and cisplatin-chemoresistant
RT   retinoblastoma cell lines.";
RL   Oncol. Rep. 39:160-172(2018).
//
RX   PubMed=30584916; DOI=10.1016/j.yexcr.2018.12.018;
RA   Schwermer, Melanie
RA   Hiber, Michaela
RA   Dreesmann, Sabine
RA   Rieb, Anja
RA   Theissen, Jessica
RA   Herold, Thomas
RA   Schramm, Alexander
RA   Temming, Petra
RA   Steenpass, Laura
RT   "Comprehensive characterization of RB1 mutant and MYCN amplified
RT   retinoblastoma cell lines.";
RL   Exp. Cell Res. 375:92-99(2019).
//