ID RB355 AC CVCL_S611 SY RB 355; RB-355 DR cancercelllines; CVCL_S611 DR Wikidata; Q54949306 RX PubMed=1679230; RX PubMed=1682862; RX PubMed=2090524; RX PubMed=2365495; RX PubMed=2751270; RX PubMed=2917337; RX PubMed=4018796; RX PubMed=23498719; RX PubMed=25326674; RX PubMed=29192327; RX PubMed=30584916; CC Problematic cell line: Contaminated. Shown to be a Y-79 derivative (PubMed=1679230). Originally thought to originate from a male patient with retinoblastoma. CC Population: Caucasian. CC Doubling time: 81.4 +- 5.7 hours (PubMed=2751270); 66 hours (PubMed=25326674). CC Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line). CC Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line). CC Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230. DI NCIt; C7541; Retinoblastoma DI ORDO; Orphanet_790; Retinoblastoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) HI CVCL_1893 ! Y-79 SX Female AG 2Y6M CA Cancer cell line DT Created: 03-02-14; Last updated: 19-12-24; Version: 20 CH CVCL_B7IH ! RB355 CDDP-R CH CVCL_B7II ! RB355 Eto-R // RX PubMed=30584916; DOI=10.1016/j.yexcr.2018.12.018; RA Schwermer, Melanie RA Hiber, Michaela RA Dreesmann, Sabine RA Rieb, Anja RA Theissen, Jessica RA Herold, Thomas RA Schramm, Alexander RA Temming, Petra RA Steenpass, Laura RT "Comprehensive characterization of RB1 mutant and MYCN amplified RT retinoblastoma cell lines."; RL Exp. Cell Res. 375:92-99(2019). // RX PubMed=2751270; RA Chan, Helen S.L. RA Canton, Marc D. RA Gallie, Brenda Louise RT "Chemosensitivity and multidrug resistance to antineoplastic drugs in RT retinoblastoma cell lines."; RL Anticancer Res. 9:469-474(1989). // RX PubMed=25326674; DOI=10.1007/s00418-014-1285-z; RA Busch, Maike Anna RA Philippeit, Claudia RA Weise, Andreas RA Dunker, Nicole RT "Re-characterization of established human retinoblastoma cell lines."; RL Histochem. Cell Biol. 143:325-338(2015). // RX PubMed=1679230; DOI=10.3109/13816819109023085; RA Madreperla, Steven A. RA Bookstein, Robert RA Jones, Oliver W. RA Lee, Wen-Hwa RT "Retinoblastoma cell lines Y79, RB355 and WERI-Rb27 are genetically RT related."; RL Ophthalmic Paediatr. Genet. 12:49-56(1991). // RX PubMed=29192327; DOI=10.3892/or.2017.6100; PMCID=PMC5783599; RA Busch, Maike Anna RA Papior, David RA Stephan, Harald RA Dunker, Nicole RT "Characterization of etoposide- and cisplatin-chemoresistant RT retinoblastoma cell lines."; RL Oncol. Rep. 39:160-172(2018). // RX PubMed=2917337; DOI=10.1016/0165-4608(89)90079-4; RA Horsthemke, Bernhard RA Greger, Valerie RA Becher, Reinhard RA Passarge, Eberhard RT "Mechanism of i(6p) formation in retinoblastoma tumor cells."; RL Cancer Genet. Cytogenet. 37:95-102(1989). // RX PubMed=2365495; DOI=10.1002/ijc.2910460123; RA Griegel, Sabine RA Hong, Chen RA Frotschl, Roland RA Hulser, Dieter F. RA Greger, Valerie RA Horsthemke, Bernhard RA Rajewsky, Manfred Fedor RT "Newly established human retinoblastoma cell lines exhibit an RT 'immortalized' but not an invasive phenotype in vitro."; RL Int. J. Cancer 46:125-132(1990). // RX PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x; RA Griegel, Sabine RA Heise, Kerstin RA Kindler-Rohrborn, Andrea RA Rajewsky, Manfred Fedor RT "In vitro differentiation of human retinoblastoma cells into neuronal RT phenotypes."; RL Differentiation 45:250-257(1990). // RX PubMed=23498719; DOI=10.1016/S1470-2045(13)70045-7; RA Rushlow, Diane E. RA Mol, Berber M. RA Kennett, Jennifer Y. RA Yee, Stephanie RA Pajovic, Sanja RA Theriault, Brigitte L. RA Prigoda-Lee, Nadia L. RA Spencer, Clarellen RA Dimaras, Helen RA Corson, Timothy W. RA Pang, Renee RA Massey, Christine RA Godbout, Roseline RA Jiang, Zhe RA Zacksenhaus, Eldad RA Paton, Katherine RA Moll, Annette C. RA Houdayer, Claude RA Raizis, Anthony RA Halliday, William RA Lam, Wan L. RA Boutros, Paul Christopher RA Lohmann, Dietmar R. RA Dorsman, Josephine C. RA Gallie, Brenda Louise RT "Characterisation of retinoblastomas without RB1 mutations: genomic, RT gene expression, and clinical studies."; RL Lancet Oncol. 14:327-334(2013). // RX PubMed=1682862; DOI=10.1016/S0161-6420(91)32134-1; RA Chan, Helen S.L. RA Thorner, Paul Scott RA Haddad, George RA Gallie, Brenda Louise RT "Multidrug-resistant phenotype in retinoblastoma correlates with RT P-glycoprotein expression."; RL Ophthalmology 98:1425-1431(1991). // RX PubMed=4018796; DOI=10.1007/BF00295364; RA Squire, Jeremy Andrew RA Gallie, Brenda Louise RA Phillips, Robert A. RT "A detailed analysis of chromosomal changes in heritable and RT non-heritable retinoblastoma."; RL Hum. Genet. 70:291-301(1985). //