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Cellosaurus Hepa-1 (CVCL_S550)

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Cell line name Hepa-1
Synonyms Hepa 1; Hepa1
Accession CVCL_S550
Resource Identification Initiative To cite this cell line use: Hepa-1 (RRID:CVCL_S550)
Comments Characteristics: Established from a transplantable mouse hepatoma BW7756 (PubMed=6102619).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57L/J.
Hierarchy Children:
CVCL_0327 (Hepa 1-6)CVCL_0328 (Hepa-1c1c7)
Originate from same individual CVCL_E4AK ! BW
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=4362668; DOI=10.1016/0012-1606(73)90008-0
Hans Peter Bernhard, Gretchen J. Darlington, Francis Hugh Ruddle;
Expression of liver phenotypes in cultured mouse hepatoma cells: synthesis and secretion of serum albumin.
Dev. Biol. 35:83-96(1973)

PubMed=106390; DOI=10.1073/pnas.76.1.373; PMCID=PMC382941
Oliver Hankinson;
Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase.
Proc. Natl. Acad. Sci. U.S.A. 76:373-376(1979)

PubMed=6102619; DOI=10.1093/jnci/64.4.809
Gretchen J. Darlington, Hans Peter Bernhard, Richard A. Miller, Francis Hugh Ruddle;
Expression of liver phenotypes in cultured mouse hepatoma cells.
J. Natl. Cancer Inst. 64:809-819(1980)

PubMed=3431441; DOI=10.1016/s0076-6879(87)51006-0
Gretchen J. Darlington;
Liver cell lines.
Methods Enzymol. 151:19-38(1987)

Cross-references
Anatomy/cell type resources BTO; BTO_0003319
Encyclopedic resources Wikidata; Q54882811
Entry history
Entry creation03-Feb-2014
Last entry update14-Aug-2025
Version number12