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Cellosaurus M-07e/TPO (CVCL_RM07)

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Cell line name M-07e/TPO
Accession CVCL_RM07
Resource Identification Initiative To cite this cell line use: M-07e/TPO (RRID:CVCL_RM07)
Comments Population: Caucasian.
Characteristics: TPO dependent.
Doubling time: 59 +- 10 hours (PubMed=9096695).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:31677; ANO7 + HGNC; HGNC:17887; DHDH; Name(s)=ANO7-DHDH (from parent cell line).
  • Gene fusion; HGNC; HGNC:1537; CBFA2T3 + HGNC; HGNC:29450; GLIS2; Name(s)=CBFA2T3-GLIS2, ETO2-GLIS2 (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Childhood acute megakaryoblastic leukemia (NCIt: C7972)
Acute megakaryoblastic leukemia (ORDO: Orphanet_518)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2106 (M-07e)
Sex of cell Female
Age at sampling 6M
Category Cancer cell line
Publications

PubMed=9096695; DOI=10.1038/sj.leu.2400621
Hans Gunther Drexler, Margarete Zaborski, Hilmar Quentmeier;
Thrombopoietin supports the continuous growth of cytokine-dependent human leukemia cell lines.
Leukemia 11:541-551(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RM07
Encyclopedic resources Wikidata; Q54903380
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number10