ID   M-07e/TPO
AC   CVCL_RM07
DR   cancercelllines; CVCL_RM07
DR   Wikidata; Q54903380
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=9096695;
CC   Population: Caucasian.
CC   Characteristics: TPO dependent.
CC   Doubling time: 59 +- 10 hours (PubMed=9096695).
CC   Sequence variation: Gene fusion; HGNC; 31677; ANO7 + HGNC; 17887; DHDH; Name(s)=ANO7-DHDH (from parent cell line).
CC   Sequence variation: Gene fusion; HGNC; 1537; CBFA2T3 + HGNC; 29450; GLIS2; Name(s)=CBFA2T3-GLIS2, ETO2-GLIS2 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C7972; Childhood acute megakaryoblastic leukemia
DI   ORDO; Orphanet_518; Acute megakaryoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2106 ! M-07e
SX   Female
AG   6M
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 05-10-23; Version: 9
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001).
//
RX   PubMed=9096695; DOI=10.1038/sj.leu.2400621;
RA   Drexler H.G., Zaborski M., Quentmeier H.;
RT   "Thrombopoietin supports the continuous growth of cytokine-dependent
RT   human leukemia cell lines.";
RL   Leukemia 11:541-551(1997).
//