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Cellosaurus MKN45G (CVCL_RM02)

[Text version]
Cell line name MKN45G
Accession CVCL_RM02
Resource Identification Initiative To cite this cell line use: MKN45G (RRID:CVCL_RM02)
Comments Population: Japanese.
Characteristics: Gastrin-producing. Established through nine passages of the parent cell line in hypergastrinaemic nude mice.
Doubling time: 16 hours (PubMed=2105279).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line

PubMed=2105279; DOI=10.1002/ijc.2910450117
Watson S.A., Durrant L.G., Morris D.L.
The effect of the E2 prostaglandin enprostil, and the somatostatin analogue SMS 201 995, on the growth of a human gastric cell line, MKN45G.
Int. J. Cancer 45:90-94(1990)

PubMed=2061947; DOI=10.1093/jnci/83.12.866
Watson S.A., Durrant L.G., Wencyk P.M., Watson A.L., Morris D.L.
Intracellular gastrin in human gastrointestinal tumor cells.
J. Natl. Cancer Inst. 83:866-871(1991)

Cell line databases/resources cancercelllines; CVCL_RM02
Encyclopedic resources Wikidata; Q54905827
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number9