ID   MKN45G
AC   CVCL_RM02
DR   cancercelllines; CVCL_RM02
DR   Wikidata; Q54905827
RX   PubMed=2061947;
RX   PubMed=2105279;
CC   Population: Japanese.
CC   Characteristics: Gastrin-producing. Established through nine passages of the parent cell line in hypergastrinaemic nude mice.
CC   Doubling time: 16 hours (PubMed=2105279).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
DI   NCIt; C4004; Gastric adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0434 ! MKN45
SX   Female
AG   62Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 05-10-23; Version: 9
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RX   PubMed=2061947; DOI=10.1093/jnci/83.12.866;
RA   Watson S.A., Durrant L.G., Wencyk P.M., Watson A.L., Morris D.L.;
RT   "Intracellular gastrin in human gastrointestinal tumor cells.";
RL   J. Natl. Cancer Inst. 83:866-871(1991).
//
RX   PubMed=2105279; DOI=10.1002/ijc.2910450117;
RA   Watson S.A., Durrant L.G., Morris D.L.;
RT   "The effect of the E2 prostaglandin enprostil, and the somatostatin
RT   analogue SMS 201 995, on the growth of a human gastric cell line,
RT   MKN45G.";
RL   Int. J. Cancer 45:90-94(1990).
//