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Cellosaurus MEF3.8 (CVCL_R997)

[Text version]
Cell line name MEF3.8
Synonyms Mef3.8
Accession CVCL_R997
Resource Identification Initiative To cite this cell line use: MEF3.8 (RRID:CVCL_R997)
Comments Knockout cell: Method=KO mouse; MGI; MGI:97570; Abcb1a.
Knockout cell: Method=KO mouse; MGI; MGI:97568; Abcb1b.
Knockout cell: Method=KO mouse; MGI; MGI:102676; Abcc1.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Children:
CVCL_R999 (MEF3.8/M32)CVCL_R998 (MEF3.8/T6400)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=10485464
Allen J.D., Brinkhuis R.F., Wijnholds J., Schinkel A.H.
The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin.
Cancer Res. 59:4237-4241(1999)

PubMed=11059771
Allen J.D., Brinkhuis R.F., van Deemter L., Wijnholds J., Schinkel A.H.
Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance.
Cancer Res. 60:5761-5766(2000)

PubMed=11956086
Allen J.D., Jackson S.C., Schinkel A.H.
A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance.
Cancer Res. 62:2294-2299(2002)

Cross-references
Encyclopedic resources Wikidata; Q54905032
Entry history
Entry creation05-Nov-2013
Last entry update29-Jun-2023
Version number7