ID   MEF3.8
AC   CVCL_R997
SY   Mef3.8
DR   Wikidata; Q54905032
RX   PubMed=10485464;
RX   PubMed=11059771;
RX   PubMed=11956086;
CC   Knockout cell: Method=KO mouse; MGI; MGI:97570; Abcb1a.
CC   Knockout cell: Method=KO mouse; MGI; MGI:97568; Abcb1b.
CC   Knockout cell: Method=KO mouse; MGI; MGI:102676; Abcc1.
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 05-11-13; Last updated: 29-06-23; Version: 7
//
RX   PubMed=10485464;
RA   Allen J.D., Brinkhuis R.F., Wijnholds J., Schinkel A.H.;
RT   "The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in
RT   cell lines selected for resistance to topotecan, mitoxantrone, or
RT   doxorubicin.";
RL   Cancer Res. 59:4237-4241(1999).
//
RX   PubMed=11059771;
RA   Allen J.D., Brinkhuis R.F., van Deemter L., Wijnholds J.,
RA   Schinkel A.H.;
RT   "Extensive contribution of the multidrug transporters P-glycoprotein
RT   and Mrp1 to basal drug resistance.";
RL   Cancer Res. 60:5761-5766(2000).
//
RX   PubMed=11956086;
RA   Allen J.D., Jackson S.C., Schinkel A.H.;
RT   "A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in
RT   mouse cell lines selected for doxorubicin resistance.";
RL   Cancer Res. 62:2294-2299(2002).
//