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Cellosaurus HuO9-M112 (CVCL_R725)

[Text version]
Cell line name HuO9-M112
Synonyms Hu09-M112; M112
Accession CVCL_R725
Resource Identification Initiative To cite this cell line use: HuO9-M112 (RRID:CVCL_R725)
Comments Population: Japanese.
Characteristics: Highly metastatic.
Doubling time: 42.4 hours (PubMed=14669798).
Omics: H3K4me1 ChIP-seq epigenome analysis.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone, right distal femur; UBERON=UBERON_0004406.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1298 (HuO9)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=12405284; DOI=10.1023/A:1020395816633
Kimura K., Nakano T., Park Y.-B., Tani M., Tsuda H., Beppu Y., Moriya H., Yokota J.
Establishment of human osteosarcoma cell lines with high metastatic potential to lungs and their utilities for therapeutic studies on metastatic osteosarcoma.
Clin. Exp. Metastasis 19:477-485(2002)

PubMed=14669798; DOI=10.1023/A:1027355610603
Nakano T., Tani M., Ishibashi Y., Kimura K., Park Y.-B., Imaizumi N., Tsuda H., Aoyagi K., Sasaki H., Ohwada S., Yokota J.
Biological properties and gene expression associated with metastatic potential of human osteosarcoma.
Clin. Exp. Metastasis 20:665-674(2003)

PubMed=26320182; DOI=10.18632/oncotarget.5177
Ren L., Mendoza A., Zhu J., Briggs J.W., Halsey C., Hong E.S., Burkett S.S., Morrow J.J., Lizardo M.M., Osborne T., Li S.Q., Luu H.H., Meltzer P.S., Khanna C.
Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.
Oncotarget 6:29469-29481(2015)

PubMed=29334376; DOI=10.1038/nm.4475
Morrow J.J., Bayles I., Funnell A.P.W., Miller T.E., Saiakhova A., Lizardo M.M., Bartels C.F., Kapteijn M.Y., Hung S., Mendoza A., Dhillon G., Chee D.R., Myers J.T., Allen F., Gambarotti M., Righi A., DiFeo A., Rubin B.P., Huang A.Y., Meltzer P.S., Helman L.J., Picci P., Versteeg H., Stamatoyannopoulos J.A., Khanna C., Scacheri P.C.
Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.
Nat. Med. 24:176-185(2018)

Cross-references
Encyclopedic resources Wikidata; Q54896888
Gene expression databases GEO; GSM1914996
GEO; GSM1914997
GEO; GSM1914998
GEO; GSM1914999
Entry history
Entry creation05-Nov-2013
Last entry update29-Jun-2023
Version number10