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Cellosaurus HuO9-M112 (CVCL_R725)

[Text version]
Cell line name HuO9-M112
Synonyms Hu09-M112; M112
Accession CVCL_R725
Resource Identification Initiative To cite this cell line use: HuO9-M112 (RRID:CVCL_R725)
Comments Population: Japanese.
Characteristics: Highly metastatic.
Doubling time: 42.4 hours (PubMed=14669798).
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K4me1.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone, right distal femur; UBERON=UBERON_0004406.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1298 (HuO9)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=12405284; DOI=10.1023/A:1020395816633
Kenji Kimura, Tetsuhiro Nakano, Yong-Bum Park, Masachika Tani, Hiroyuki Tsuda, Yasuo Beppu, Hideshige Moriya, Jun Yokota;
Establishment of human osteosarcoma cell lines with high metastatic potential to lungs and their utilities for therapeutic studies on metastatic osteosarcoma.
Clin. Exp. Metastasis 19:477-485(2002)

PubMed=14669798; DOI=10.1023/A:1027355610603
Tetsuhiro Nakano, Masachika Tani, Yasunori Ishibashi, Kenji Kimura, Yong-Bum Park, Natsuko Imaizumi, Hiroyuki Tsuda, Kazuhiko Aoyagi, Hiroki Sasaki, Susumu Ohwada, Jun Yokota;
Biological properties and gene expression associated with metastatic potential of human osteosarcoma.
Clin. Exp. Metastasis 20:665-674(2003)

PubMed=26320182; DOI=10.18632/oncotarget.5177; PMCID=PMC4745740
Ling Ren, Arnulfo Mendoza, Jack Zhu, Joseph W. Briggs, Charles Halsey, Ellen S. Hong, Sandra Sczerba Burkett, James J. Morrow, Michael M. Lizardo, Tanasa Osborne, Samuel Q. Li ...Show all 14 authors... , Hue H. Luu, Paul S. Meltzer, Chand Khanna; Show fewer authors
Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.
Oncotarget 6:29469-29481(2015)

PubMed=29334376; DOI=10.1038/nm.4475; PMCID=PMC5803371
James J. Morrow, Ian Bayles, Alister Peter William Funnell, Tyler Eugene Miller, Alina Saiakhova, Michael M. Lizardo, Cynthia F. Bartels, Maaike Y. Kapteijn, Stevephen Hung, Arnulfo Mendoza, Gursimran Dhillon ...Show all 26 authors... , Daniel R. Chee, Jay T. Myers, Frederick Allen, Marco Gambarotti, Alberto Righi, Analisa DiFeo, Brian P. Rubin, Alex Y. Huang, Paul S. Meltzer, Lee J. Helman, Piero Picci, Hendrik Henri Versteeg, John A. Stamatoyannopoulos, Chand Khanna, Peter C. Scacheri; Show fewer authors
Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.
Nat. Med. 24:176-185(2018)

Cross-references
Encyclopedic resources Wikidata; Q54896888
Gene expression databases GEO; GSM1914996
GEO; GSM1914997
GEO; GSM1914998
GEO; GSM1914999
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number11