ID   HuO9-M112
AC   CVCL_R725
SY   Hu09-M112; M112
DR   GEO; GSM1914996
DR   GEO; GSM1914997
DR   GEO; GSM1914998
DR   GEO; GSM1914999
DR   Wikidata; Q54896888
RX   PubMed=12405284;
RX   PubMed=14669798;
RX   PubMed=26320182;
RX   PubMed=29334376;
CC   Population: Japanese.
CC   Characteristics: Highly metastatic.
CC   Doubling time: 42.4 hours (PubMed=14669798).
CC   Omics: H3K4me1 ChIP-seq epigenome analysis.
CC   Omics: H3K27ac ChIP-seq epigenome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Bone, right distal femur; UBERON=UBERON_0004406.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1298 ! HuO9
SX   Female
AG   13Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 29-06-23; Version: 10
//
RX   PubMed=12405284; DOI=10.1023/A:1020395816633;
RA   Kimura K., Nakano T., Park Y.-B., Tani M., Tsuda H., Beppu Y.,
RA   Moriya H., Yokota J.;
RT   "Establishment of human osteosarcoma cell lines with high metastatic
RT   potential to lungs and their utilities for therapeutic studies on
RT   metastatic osteosarcoma.";
RL   Clin. Exp. Metastasis 19:477-485(2002).
//
RX   PubMed=14669798; DOI=10.1023/A:1027355610603;
RA   Nakano T., Tani M., Ishibashi Y., Kimura K., Park Y.-B., Imaizumi N.,
RA   Tsuda H., Aoyagi K., Sasaki H., Ohwada S., Yokota J.;
RT   "Biological properties and gene expression associated with metastatic
RT   potential of human osteosarcoma.";
RL   Clin. Exp. Metastasis 20:665-674(2003).
//
RX   PubMed=26320182; DOI=10.18632/oncotarget.5177;
RA   Ren L., Mendoza A., Zhu J., Briggs J.W., Halsey C., Hong E.S.,
RA   Burkett S.S., Morrow J.J., Lizardo M.M., Osborne T., Li S.Q.,
RA   Luu H.H., Meltzer P.S., Khanna C.;
RT   "Characterization of the metastatic phenotype of a panel of
RT   established osteosarcoma cells.";
RL   Oncotarget 6:29469-29481(2015).
//
RX   PubMed=29334376; DOI=10.1038/nm.4475;
RA   Morrow J.J., Bayles I., Funnell A.P.W., Miller T.E., Saiakhova A.,
RA   Lizardo M.M., Bartels C.F., Kapteijn M.Y., Hung S., Mendoza A.,
RA   Dhillon G., Chee D.R., Myers J.T., Allen F., Gambarotti M., Righi A.,
RA   DiFeo A., Rubin B.P., Huang A.Y., Meltzer P.S., Helman L.J., Picci P.,
RA   Versteeg H., Stamatoyannopoulos J.A., Khanna C., Scacheri P.C.;
RT   "Positively selected enhancer elements endow osteosarcoma cells with
RT   metastatic competence.";
RL   Nat. Med. 24:176-185(2018).
//