Cellosaurus logo
expasy logo

Cellosaurus G-401 BAF47 (CVCL_QW55)

[Text version]
Cell line name G-401 BAF47
Synonyms G401 BAF47; G401_BAF47
Accession CVCL_QW55
Resource Identification Initiative To cite this cell line use: G-401 BAF47 (RRID:CVCL_QW55)
Comments Problematic cell line: Misclassified. Parent cell line (G-401) was originally thought to be a Wilms tumor cell line but is a kidney rhabdoid tumor cell line.
Population: Caucasian.
Characteristics: Transduction of SMARCB1 rescues the phenotype of the parent cell line which is homozygous for its deletion (PubMed=28945250).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11103; SMARCB1 (Note=With a C-terminal V5 tag).
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease Rhabdoid tumor of the kidney (NCIt: C8715)
Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0270 (G-401)
Sex of cell Male
Age at sampling 3M
Category Cancer cell line
Publications

PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080
Robert T. Nakayama, John L. Pulice, Alfredo M. Valencia, Matthew J. McBride, Zachary M. McKenzie, Mark A. Gillespie, Wai Lim Ku, Ming-Xiang Teng, Kai-Rong Cui, Robert T. Williams, Seth H. Cassel ...Show all 18 authors... , He Qing, Christian J. Widmer, George Daniel Demetri, Rafael Angel Irizarry, Ke-Ji Zhao, Jeffrey A. Ranish, Cigall Kadoch; Show fewer authors
SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Nat. Genet. 49:1613-1623(2017)

Cross-references
Encyclopedic resources Wikidata; Q54835348
Gene expression databases GEO; GSM2409664
GEO; GSM2409665
GEO; GSM2409666
GEO; GSM2409667
GEO; GSM2409668
GEO; GSM2409669
GEO; GSM2787353
Entry history
Entry creation15-Nov-2017
Last entry update14-Aug-2025
Version number12