ID   G-401 BAF47
AC   CVCL_QW55
SY   G401 BAF47; G401_BAF47
DR   GEO; GSM2409664
DR   GEO; GSM2409665
DR   GEO; GSM2409666
DR   GEO; GSM2409667
DR   GEO; GSM2409668
DR   GEO; GSM2409669
DR   GEO; GSM2787353
DR   Wikidata; Q54835348
RX   PubMed=28945250;
CC   Problematic cell line: Misclassified. Parent cell line (G-401) was originally thought to be a Wilms tumor cell line but is a kidney rhabdoid tumor cell line.
CC   Population: Caucasian.
CC   Characteristics: Transduction of SMARCB1 rescues the phenotype of the parent cell line which is homozygous for its deletion (PubMed=28945250).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11103; SMARCB1 (Note=With a C-terminal V5 tag).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
CC   Omics: Genomics; ChIP-seq; H3K27ac.
CC   Omics: Genomics; ChIP-seq; H3K27me3.
CC   Omics: Genomics; ChIP-seq; H3K4me3.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C8715; Rhabdoid tumor of the kidney
DI   ORDO; Orphanet_69077; Rhabdoid tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0270 ! G-401
SX   Male
AG   3M
CA   Cancer cell line
DT   Created: 15-11-17; Last updated: 14-08-25; Version: 12
//
RX   PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080;
RA   Nakayama, Robert T.
RA   Pulice, John L.
RA   Valencia, Alfredo M.
RA   McBride, Matthew J.
RA   McKenzie, Zachary M.
RA   Gillespie, Mark A.
RA   Ku, Wai Lim
RA   Teng, Ming-Xiang
RA   Cui, Kai-Rong
RA   Williams, Robert T.
RA   Cassel, Seth H.
RA   Qing, He
RA   Widmer, Christian J.
RA   Demetri, George Daniel
RA   Irizarry, Rafael Angel
RA   Zhao, Ke-Ji
RA   Ranish, Jeffrey A.
RA   Kadoch, Cigall
RT   "SMARCB1 is required for widespread BAF complex-mediated activation of
RT   enhancers and bivalent promoters.";
RL   Nat. Genet. 49:1613-1623(2017).
//