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Cellosaurus 41M-cisR (CVCL_N788)

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Cell line name 41M-cisR
Synonyms 41M/cisR; 41McisR
Accession CVCL_N788
Resource Identification Initiative To cite this cell line use: 41M-cisR (RRID:CVCL_N788)
Comments Problematic cell line: Contaminated. Parent cell line (41M) has been shown to be a OAW28 derivative.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Omics: Transcriptomics; Microarray.
Misspelling: M41CisR; GEO=GSM851923.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Argfs*18 (c.455delC); ClinVar=VCV000634779; Zygosity=Unspecified (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4993 (41M)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): PubMed=22710073

Markers:
AmelogeninX
CSF1PO11
D2S133820,23
D3S135814,18
D5S81812
D7S82011
D8S117911,15
D13S31711
D16S53913
D18S5112,14
D19S43313
D21S1129
FGA21,24
TH019
TPOX8
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=1617660
Lloyd R. Kelland, Prakash Mistry, George Abel, Swee Y. Loh, Ciaran F. O'Neill, Barry A. Murrer, Kenneth Reginald Harrap;
Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.
Cancer Res. 52:3857-3864(1992)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Christopher T. Korch, Monique A. Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford;
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_N788
Chemistry resources ChEMBL-Cells; CHEMBL3989321
PubChem_Cell_line; CVCL_N788
Encyclopedic resources Wikidata; Q54602997
Gene expression databases GEO; GSM851923
Polymorphism and mutation databases Cosmic; 1609533
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number24