ID   41M-cisR
AC   CVCL_N788
SY   41M/cisR; 41McisR
DR   cancercelllines; CVCL_N788
DR   ChEMBL-Cells; CHEMBL3989321
DR   Cosmic; 1609533
DR   GEO; GSM851923
DR   PubChem_Cell_line; CVCL_N788
DR   Wikidata; Q54602997
RX   PubMed=1617660;
RX   PubMed=22710073;
CC   Problematic cell line: Contaminated. Parent cell line (41M) has been shown to be a OAW28 derivative.
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Pro152Argfs*18 (c.455delC); ClinVar=VCV000634779; Zygosity=Unspecified (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Misspelling: M41CisR; GEO=GSM851923.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): PubMed=22710073
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 13
ST   D18S51: 12,14
ST   D19S433: 13
ST   D21S11: 29
ST   D2S1338: 20,23
ST   D3S1358: 14,18
ST   D5S818: 12
ST   D7S820: 11
ST   D8S1179: 11,15
ST   FGA: 21,24
ST   TH01: 9
ST   TPOX: 8
ST   vWA: 17,19
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4993 ! 41M
SX   Female
AG   75Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 05-10-23; Version: 22
RX   PubMed=1617660;
RA   Kelland L.R., Mistry P., Abel G., Loh S.Y., O'Neill C.F., Murrer B.A.,
RA   Harrap K.R.;
RT   "Mechanism-related circumvention of acquired
RT   cis-diamminedichloroplatinum(II) resistance using two pairs of human
RT   ovarian carcinoma cell lines by ammine/amine platinum(IV)
RT   dicarboxylates.";
RL   Cancer Res. 52:3857-3864(1992).
RX   PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017;
RA   Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K.,
RA   Lessey B.A., Jordan V.C., Bradford A.P.;
RT   "DNA profiling analysis of endometrial and ovarian cell lines reveals
RT   misidentification, redundancy and contamination.";
RL   Gynecol. Oncol. 127:241-248(2012).