ID   41M-cisR
AC   CVCL_N788
SY   41M/cisR; 41McisR
DR   cancercelllines; CVCL_N788
DR   ChEMBL-Cells; CHEMBL3989321
DR   Cosmic; 1609533
DR   GEO; GSM851923
DR   PubChem_Cell_line; CVCL_N788
DR   Wikidata; Q54602997
RX   PubMed=1617660;
RX   PubMed=22710073;
CC   Problematic cell line: Contaminated. Parent cell line (41M) has been shown to be a OAW28 derivative.
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Argfs*18 (c.455delC); ClinVar=VCV000634779; Zygosity=Unspecified (from parent cell line).
CC   Omics: Transcriptomics; Microarray.
CC   Misspelling: M41CisR; GEO=GSM851923.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): PubMed=22710073
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 13
ST   D18S51: 12,14
ST   D19S433: 13
ST   D21S11: 29
ST   D2S1338: 20,23
ST   D3S1358: 14,18
ST   D5S818: 12
ST   D7S820: 11
ST   D8S1179: 11,15
ST   FGA: 21,24
ST   TH01: 9
ST   TPOX: 8
ST   vWA: 17,19
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4993 ! 41M
SX   Female
AG   75Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 10-04-25; Version: 24
//
RX   PubMed=1617660;
RA   Kelland, Lloyd R.
RA   Mistry, Prakash
RA   Abel, George
RA   Loh, Swee Y.
RA   O'Neill, Ciaran F.
RA   Murrer, Barry A.
RA   Harrap, Kenneth Reginald
RT   "Mechanism-related circumvention of acquired
RT   cis-diamminedichloroplatinum(II) resistance using two pairs of human
RT   ovarian carcinoma cell lines by ammine/amine platinum(IV)
RT   dicarboxylates.";
RL   Cancer Res. 52:3857-3864(1992).
//
RX   PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677;
RA   Korch, Christopher T.
RA   Spillman, Monique Ann
RA   Jackson, Twila A.
RA   Jacobsen, Britta M.
RA   Murphy, Susan K.
RA   Lessey, Bruce Arthur
RA   Jordan, Virgil Craig
RA   Bradford, Andrew Peter
RT   "DNA profiling analysis of endometrial and ovarian cell lines reveals
RT   misidentification, redundancy and contamination.";
RL   Gynecol. Oncol. 127:241-248(2012).
//