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Cellosaurus IMR-5/75 (CVCL_M473)

[Text version]
Cell line name IMR-5/75
Synonyms IMR-5-75; IMR5/75; IMR5-75
Accession CVCL_M473
Resource Identification Initiative To cite this cell line use: IMR-5/75 (RRID:CVCL_M473)
Comments Population: Caucasian.
Omics: Transcriptomics; RNAseq; Single cell.
Miscellaneous: STR profile from personal communication of Henssen, Anton George & Roefzaad, Claudia.
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1306 (IMR-5)
Sex of cell Male
Age at sampling 1Y1M
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133823,24
D3S135816
D5S81811,12
D7S8209,10
D8S117913
D13S3179
D16S5398
D18S5112,15
D19S43314,15
D21S1130,31
FGA21,24
TH017,9.3
TPOX11
vWA15

Run an STR similarity search on this cell line
Publications

PubMed=16216448; DOI=10.1016/j.gene.2005.07.038
Andre Oberthuer, Matthias Skowron, Rudiger Spitz, Yvonne Kahlert, Frank Westermann, Kathrin Mehler, Frank Berthold, Matthias Fischer;
Characterization of a complex genomic alteration on chromosome 2p that leads to four alternatively spliced fusion transcripts in the neuroblastoma cell lines IMR-5, IMR-5/75 and IMR-32.
Gene 363:41-50(2005)

PubMed=39255063; DOI=10.1016/j.celrep.2024.114711
Maja-Celine Stober, Rocio Chamorro Gonzalez, Lotte Bruckner, Thomas Conrad, Nadine Wittstruck, Annabell Krienelke Szymansky, Angelika Eggert, Johannes Hubertus Schulte, Richard Patrick Koche, Anton George Henssen, Roland F. Schwarz, Kerstin Haase;
Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity.
Cell Rep. 43:114711.1-114711.19(2024)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL4523519
ChEMBL-Targets; CHEMBL4523550
PubChem_Cell_line; CVCL_M473
Encyclopedic resources Wikidata; Q54897649
Polymorphism and mutation databases Cosmic; 2393631
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number14