ID   IMR-5/75
AC   CVCL_M473
SY   IMR-5-75; IMR5/75; IMR5-75
DR   ChEMBL-Cells; CHEMBL4523519
DR   ChEMBL-Targets; CHEMBL4523550
DR   Cosmic; 2393631
DR   PubChem_Cell_line; CVCL_M473
DR   Wikidata; Q54897649
RX   PubMed=16216448;
RX   PubMed=39255063;
CC   Population: Caucasian.
CC   Omics: Transcriptomics; RNAseq; Single cell.
CC   Miscellaneous: STR profile from personal communication of Henssen, Anton George and Roefzaad, Claudia.
CC   Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 9
ST   D16S539: 8
ST   D18S51: 12,15
ST   D19S433: 14,15
ST   D21S11: 30,31
ST   D2S1338: 23,24
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D7S820: 9,10
ST   D8S1179: 13
ST   FGA: 21,24
ST   TH01: 7,9.3
ST   TPOX: 11
ST   vWA: 15
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1306 ! IMR-5
SX   Male
AG   1Y1M
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 10-04-25; Version: 13
//
RX   PubMed=16216448; DOI=10.1016/j.gene.2005.07.038;
RA   Oberthuer A., Skowron M., Spitz R., Kahlert Y., Westermann F.,
RA   Mehler K., Berthold F., Fischer M.;
RT   "Characterization of a complex genomic alteration on chromosome 2p
RT   that leads to four alternatively spliced fusion transcripts in the
RT   neuroblastoma cell lines IMR-5, IMR-5/75 and IMR-32.";
RL   Gene 363:41-50(2005).
//
RX   PubMed=39255063; DOI=10.1016/j.celrep.2024.114711;
RA   Stober M.-C., Chamorro Gonzalez R., Bruckner L., Conrad T., Wittstruck N.,
RA   Krienelke Szymansky A., Eggert A., Schulte J.H., Koche R.P.,
RA   Henssen A.G., Schwarz R.F., Haase K.;
RT   "Intercellular extrachromosomal DNA copy-number heterogeneity drives
RT   neuroblastoma cell state diversity.";
RL   Cell Rep. 43:114711.1-114711.19(2024).
//