Cellosaurus cell line EJ-30 clone B3 (CVCL

Cellosaurus EJ-30 clone B3 (CVCL_LN36)

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Cell line name

EJ-30 clone B3

Synonyms

Accession

CVCL_LN36

Resource Identification Initiative

To cite this cell line use: EJ-30 clone B3 (RRID:CVCL_LN36)

Comments

Problematic cell line: Contaminated. Grand-parent cell line (Ej138) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.

Sequence variations

Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).

Disease

Bladder carcinoma (NCIt: C4912)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_LN34 (EJ-30)
Children:

CVCL_LN37 (EJ-30 clone B3-WrnDN1)

Sex of cell

Female

Age at sampling

82Y