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Cellosaurus C5065 (CVCL_LB79)

[Text version]
Cell line name C5065
Synonyms DFT1.C5065
Accession CVCL_LB79
Resource Identification Initiative To cite this cell line use: C5065 (RRID:CVCL_LB79)
Comments Group: Marsupial cell line.
Characteristics: Originates from DFT1 strain 3.
Disease Devil facial tumor disease 1 (NCIt: C176223)
Species of origin Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius) (NCBI Taxonomy: 9305)
Originate from same individual CVCL_LB75 ! 1/2Pea
CVCL_LB76 ! 1426
CVCL_LB77 ! 2112
CVCL_LB78 ! 4906
Sex of cell Female
Category Cancer cell line

PubMed=23479617; DOI=10.1073/pnas.1219920110
Siddle H.V.T., Kreiss A., Tovar C., Yuen C.K., Cheng Y., Belov K., Swift K., Pearse A.-M., Hamede R., Jones M.E., Skjodt K., Woods G.M., Kaufman J.
Reversible epigenetic down-regulation of MHC molecules by devil facial tumour disease illustrates immune escape by a contagious cancer.
Proc. Natl. Acad. Sci. U.S.A. 110:5103-5108(2013)

PubMed=25708088; DOI=10.1016/j.vaccine.2015.01.039
Kreiss A., Brown G.K., Tovar C., Lyons A.B., Woods G.M.
Evidence for induction of humoral and cytotoxic immune responses against devil facial tumor disease cells in Tasmanian devils (Sarcophilus harrisii) immunized with killed cell preparations.
Vaccine 33:3016-3025(2015)

PubMed=27936237; DOI=10.1371/journal.pone.0168068
Patchett A.L., Darby J.M., Tovar C., Lyons A.B., Woods G.M.
The immunomodulatory small molecule imiquimod induces apoptosis in devil facial tumour cell lines.
PLoS ONE 11:E0168068-E0168068(2016)

PubMed=32937435; DOI=10.1126/sciadv.aba5031
Flies A.S., Darby J.M., Lennard P.R., Murphy P.R., Ong C.E.B., Pinfold T.L., De Luca A., Lyons A.B., Woods G.M., Patchett A.L.
A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers.
Sci. Adv. 6:eaba5031.1-eaba5031.13(2020)

Encyclopedic resources Wikidata; Q54808194
Entry history
Entry creation22-Aug-2017
Last entry update21-Mar-2023
Version number4