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Cellosaurus C5065 (CVCL_LB79)

[Text version]
Cell line name C5065
Synonyms DFT1.C5065
Accession CVCL_LB79
Resource Identification Initiative To cite this cell line use: C5065 (RRID:CVCL_LB79)
Comments Group: Marsupial cell line.
Characteristics: Originates from DFT1 strain 3.
Disease Devil facial tumor disease 1 (NCIt: C176223)
Species of origin Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius) (NCBI Taxonomy: 9305)
Originate from same individual CVCL_LB75 ! 1/2Pea
CVCL_LB76 ! 1426
CVCL_LB77 ! 2112
CVCL_LB78 ! 4906
Sex of cell Female
Category Cancer cell line
Publications

PubMed=23479617; DOI=10.1073/pnas.1219920110; PMCID=PMC3612627
Hannah V.T. Siddle, Alexandre Kreiss, Cesar Dario Tovar Lopez, Chun Kit Yuen, Yuan-Yuan Cheng, Katherine Belov, Kate Swift, Anne-Maree Pearse, Rodrigo Hamede, Menna E. Jones, Karsten Skjodt ...Show all 13 authors... , Gregory M. Woods, Jim Kaufman; Show fewer authors
Reversible epigenetic down-regulation of MHC molecules by devil facial tumour disease illustrates immune escape by a contagious cancer.
Proc. Natl. Acad. Sci. U.S.A. 110:5103-5108(2013)

PubMed=25708088; DOI=10.1016/j.vaccine.2015.01.039
Alexandre Kreiss, Gabriella Kathleen Brown, Cesar Dario Tovar Lopez, Alan Bruce Lyons, Gregory M. Woods;
Evidence for induction of humoral and cytotoxic immune responses against devil facial tumor disease cells in Tasmanian devils (Sarcophilus harrisii) immunized with killed cell preparations.
Vaccine 33:3016-3025(2015)

PubMed=27936237; DOI=10.1371/journal.pone.0168068; PMCID=PMC5148113
Amanda L. Patchett, Jocelyn M. Darby, Cesar Dario Tovar Lopez, Alan Bruce Lyons, Gregory M. Woods;
The immunomodulatory small molecule imiquimod induces apoptosis in devil facial tumour cell lines.
PLoS ONE 11:e0168068.1-e0168068.17(2016)

PubMed=32937435; DOI=10.1126/sciadv.aba5031; PMCID=PMC7458443
Andrew S. Flies, Jocelyn M. Darby, Patrick Roger Lennard, Peter R. Murphy, Chrissie Ee Been Ong, Terry L. Pinfold, Alana De Luca, Alan Bruce Lyons, Gregory M. Woods, Amanda L. Patchett;
A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers.
Sci. Adv. 6:eaba5031.1-eaba5031.13(2020)

Cross-references
Encyclopedic resources Wikidata; Q54808194
Entry history
Entry creation22-Aug-2017
Last entry update21-Mar-2023
Version number4