ID   C5065
AC   CVCL_LB79
SY   DFT1.C5065
DR   Wikidata; Q54808194
RX   PubMed=23479617;
RX   PubMed=25708088;
RX   PubMed=27936237;
RX   PubMed=32937435;
CC   Group: Marsupial cell line.
CC   Characteristics: Originates from DFT1 strain 3.
DI   NCIt; C176223; Devil facial tumor disease 1
OX   NCBI_TaxID=9305; ! Sarcophilus harrisii (Tasmanian devil)
OI   CVCL_LB75 ! 1/2Pea
OI   CVCL_LB76 ! 1426
OI   CVCL_LB77 ! 2112
OI   CVCL_LB78 ! 4906
SX   Female
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 21-03-23; Version: 4
//
RX   PubMed=23479617; DOI=10.1073/pnas.1219920110; PMCID=PMC3612627;
RA   Siddle, Hannah V.T.
RA   Kreiss, Alexandre
RA   Tovar Lopez, Cesar Dario
RA   Yuen, Chun Kit
RA   Cheng, Yuan-Yuan
RA   Belov, Katherine
RA   Swift, Kate
RA   Pearse, Anne-Maree
RA   Hamede, Rodrigo
RA   Jones, Menna E.
RA   Skjodt, Karsten
RA   Woods, Gregory M.
RA   Kaufman, Jim
RT   "Reversible epigenetic down-regulation of MHC molecules by devil
RT   facial tumour disease illustrates immune escape by a contagious
RT   cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:5103-5108(2013).
//
RX   PubMed=25708088; DOI=10.1016/j.vaccine.2015.01.039;
RA   Kreiss, Alexandre
RA   Brown, Gabriella Kathleen
RA   Tovar Lopez, Cesar Dario
RA   Lyons, Alan Bruce
RA   Woods, Gregory M.
RT   "Evidence for induction of humoral and cytotoxic immune responses
RT   against devil facial tumor disease cells in Tasmanian devils
RT   (Sarcophilus harrisii) immunized with killed cell preparations.";
RL   Vaccine 33:3016-3025(2015).
//
RX   PubMed=32937435; DOI=10.1126/sciadv.aba5031; PMCID=PMC7458443;
RA   Flies, Andrew S.
RA   Darby, Jocelyn M.
RA   Lennard, Patrick Roger
RA   Murphy, Peter R.
RA   Ong, Chrissie Ee Been
RA   Pinfold, Terry L.
RA   De Luca, Alana
RA   Lyons, Alan Bruce
RA   Woods, Gregory M.
RA   Patchett, Amanda L.
RT   "A novel system to map protein interactions reveals evolutionarily
RT   conserved immune evasion pathways on transmissible cancers.";
RL   Sci. Adv. 6:eaba5031.1-eaba5031.13(2020).
//
RX   PubMed=27936237; DOI=10.1371/journal.pone.0168068; PMCID=PMC5148113;
RA   Patchett, Amanda L.
RA   Darby, Jocelyn M.
RA   Tovar Lopez, Cesar Dario
RA   Lyons, Alan Bruce
RA   Woods, Gregory M.
RT   "The immunomodulatory small molecule imiquimod induces apoptosis in
RT   devil facial tumour cell lines.";
RL   PLoS ONE 11:e0168068.1-e0168068.17(2016).
//