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Cellosaurus P-STS (CVCL_L298)

[Text version]
Cell line name P-STS
Synonyms PSTS
Accession CVCL_L298
Resource Identification Initiative To cite this cell line use: P-STS (RRID:CVCL_L298)
Comments Doubling time: ~4 days (PubMed=19528452); ~1 week (PubMed=28465562).
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Small intestine, ileum; UBERON=UBERON_0002116.
Sequence variations
Disease Midgut neuroendocrine tumor G1 (NCIt: C6422)
Carcinoid syndrome (ORDO: Orphanet_100093)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L296 ! H-STS
CVCL_L297 ! L-STS
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): PubMed=29444910

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81812
D7S82010,13
D13S3178,13
D16S53912,13
D21S1129,31
TH019,9.3
TPOX8
vWA20,21,22

Run an STR similarity search on this cell line
Publications

PubMed=19528452
Roswitha Pfragner, Annemarie Behmel, Harald Hoger, Alfred Beham, Elisabeth Ingolic, Ingeborg Stelzer, Bernhard Svejda, Victor Aguiriano Moser, Anna Christina Obenauf, Veronika Siegl, Oskar Arthur Haas, Bruno Niederle;
Establishment and characterization of three novel cell lines -- P-STS, L-STS, H-STS -- derived from a human metastatic midgut carcinoid.
Anticancer Res. 29:1951-1961(2009)

PubMed=22538498; DOI=10.1159/000338793
Simona Grozinsky-Glasberg, Ilan Shimon, Hadara Rubinfeld;
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

PubMed=28465562; DOI=10.1038/s41598-017-01453-5; PMCID=PMC5430954
Beatrix Pfanzagl, Diana Mechtcheriakova, Anastasia Meshcheryakova, Stephan W. Aberle, Roswitha Pfragner, Erika Jensen-Jarolim;
Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R.
Sci. Rep. 7:1313-1313(2017)

PubMed=29444910; DOI=10.1530/ERC-17-0445; PMCID=PMC5827037
Tobias Hofving, Yvonne Arvidsson, Bilal Almobarak, Linda Inge, Roswitha Pfragner, Marta Persson, Goran Stenman, Erik Kristiansson, Viktor Johanson, Ola Nilsson;
The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.
Endocr. Relat. Cancer 25:367-380(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L298
Chemistry resources PharmacoDB; PSTS_1278_2019
Encyclopedic resources Wikidata; Q54937197
Gene expression databases GEO; GSM966945
Polymorphism and mutation databases Progenetix; CVCL_L298
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number19