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Cellosaurus P-STS (CVCL_L298)

[Text version]
Cell line name P-STS
Synonyms PSTS
Accession CVCL_L298
Resource Identification Initiative To cite this cell line use: P-STS (RRID:CVCL_L298)
Comments Doubling time: ~4 days (PubMed=19528452); ~1 week (PubMed=28465562).
Omics: Array-based CGH.
Omics: SNP array analysis.
Derived from site: In situ; Small intestine, ileum; UBERON=UBERON_0002116.
Sequence variations
Disease Midgut neuroendocrine tumor G1 (NCIt: C6422)
Carcinoid syndrome (ORDO: Orphanet_100093)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L296 ! H-STS
CVCL_L297 ! L-STS
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): PubMed=29444910

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81812
D7S82010,13
D13S3178,13
D16S53912,13
D21S1129,31
TH019,9.3
TPOX8
vWA20,21,22

Run an STR similarity search on this cell line
Publications

PubMed=19528452
Pfragner R., Behmel A., Hoger H., Beham A., Ingolic E., Stelzer I., Svejda B., Moser V.A., Obenauf A.C., Siegl V., Haas O., Niederle B.
Establishment and characterization of three novel cell lines -- P-STS, L-STS, H-STS -- derived from a human metastatic midgut carcinoid.
Anticancer Res. 29:1951-1961(2009)

PubMed=22538498; DOI=10.1159/000338793
Grozinsky-Glasberg S., Shimon I., Rubinfeld H.
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

PubMed=28465562; DOI=10.1038/s41598-017-01453-5
Pfanzagl B., Mechtcheriakova D., Meshcheryakova A., Aberle S.W., Pfragner R., Jensen-Jarolim E.
Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R.
Sci. Rep. 7:1313-1313(2017)

PubMed=29444910; DOI=10.1530/ERC-17-0445
Hofving T., Arvidsson Y., Almobarak B., Inge L., Pfragner R., Persson M., Stenman G., Kristiansson E., Johanson V., Nilsson O.
The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.
Endocr. Relat. Cancer 25:367-380(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L298
Chemistry resources PharmacoDB; PSTS_1278_2019
Encyclopedic resources Wikidata; Q54937197
Gene expression databases GEO; GSM966945
Polymorphism and mutation databases Progenetix; CVCL_L298
Entry history
Entry creation06-May-2013
Last entry update05-Oct-2023
Version number17