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Cellosaurus L-STS (CVCL_L297)

[Text version]
Cell line name L-STS
Synonyms LSTS
Accession CVCL_L297
Resource Identification Initiative To cite this cell line use: L-STS (RRID:CVCL_L297)
Comments Problematic cell line: Misclassified. Originally thought to arise from a metastatic carcinoid of the terminal ileum but shown to be an EBV-transformed lymphoblastoid cell line (PubMed=29444910; PubMed=31548718).
Doubling time: ~2 days (PubMed=19528452).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Lymph node; UBERON=UBERON_0000029.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L296 ! H-STS
CVCL_L298 ! P-STS
Sex of cell Male
Age at sampling 42Y
Category Transformed cell line
STR profile Source(s): PubMed=29444910

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,12
D7S82010,12
D13S3178,13,14
D16S53912,13
D21S1128,29,30
TH016,9,9.3
TPOX8
vWA14,17,18,19

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Publications

PubMed=19528452
Roswitha Pfragner, Annemarie Behmel, Harald Hoger, Alfred Beham, Elisabeth Ingolic, Ingeborg Stelzer, Bernhard Svejda, Victor Aguiriano Moser, Anna Christina Obenauf, Veronika Siegl, Oskar Arthur Haas, Bruno Niederle;
Establishment and characterization of three novel cell lines -- P-STS, L-STS, H-STS -- derived from a human metastatic midgut carcinoid.
Anticancer Res. 29:1951-1961(2009)

PubMed=29444910; DOI=10.1530/ERC-17-0445; PMCID=PMC5827037
Tobias Hofving, Yvonne Arvidsson, Bilal Almobarak, Linda Inge, Roswitha Pfragner, Marta Persson, Goran Stenman, Erik Kristiansson, Viktor Johanson, Ola Nilsson;
The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.
Endocr. Relat. Cancer 25:367-380(2018)

PubMed=31548718; DOI=10.1038/s41588-019-0490-z
Tobias Hofving, Joakim W. Karlsson, Ola Nilsson, Jonas A. Nilsson;
H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines.
Nat. Genet. 51:1426-1427(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L297
Encyclopedic resources Wikidata; Q54900912
Gene expression databases GEO; GSM966944
Polymorphism and mutation databases Progenetix; CVCL_L297
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number19