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Cellosaurus POE9n/TERT (CVCL_L238)

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Cell line name POE9n/TERT
Synonyms POE9n Tert; POE9n TERT
Accession CVCL_L238
Resource Identification Initiative To cite this cell line use: POE9n/TERT (RRID:CVCL_L238)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Omics: Variations; CNV analysis.
Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Cell type: Keratinocyte; CL=CL_0000312.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Disease Oral epithelial dysplasia (NCIt: C129863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_L237 (POE9n)
Sex of cell Male
Age at sampling 65Y
Category Telomerase immortalized cell line
Web pages Provider; BWH dermatology; -; https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
Publications

PubMed=10648628; DOI=10.1128/mcb.20.4.1436-1447.2000; PMCID=PMC85304
Mark A. Dickson, William Chun Hahn, Yasushi Ino, Vincent Ronfard, Jenny Y. Wu, Robert Allan Weinberg, David Neil Louis, Frederick Pei Li, James George Rheinwald;
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics.
Mol. Cell. Biol. 20:1436-1447(2000)

PubMed=25169794; DOI=10.1111/jop.12236
Christopher T.D. Dickman, Rebecca Towle, Rajan Saini, Cathie Garnis;
Molecular characterization of immortalized normal and dysplastic oral cell lines.
J. Oral Pathol. Med. 44:329-336(2015)

Cross-references
Encyclopedic resources Wikidata; Q54947699
Gene expression databases GEO; GSM1431129
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number17