ID   POE9n/TERT
AC   CVCL_L238
SY   POE9n Tert; POE9n TERT
DR   GEO; GSM1431129
DR   Wikidata; Q54947699
RX   PubMed=10648628;
RX   PubMed=25169794;
WW   Provider; BWH dermatology; -; https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
CC   Cell type: Keratinocyte; CL=CL_0000312.
DI   NCIt; C129863; Oral epithelial dysplasia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_L237 ! POE9n
SX   Male
AG   65Y
CA   Telomerase immortalized cell line
DT   Created: 06-05-13; Last updated: 10-04-25; Version: 17
//
RX   PubMed=10648628; DOI=10.1128/mcb.20.4.1436-1447.2000; PMCID=PMC85304;
RA   Dickson M.A., Hahn W.C., Ino Y., Ronfard V., Wu J.Y., Weinberg R.A.,
RA   Louis D.N., Li F.P., Rheinwald J.G.;
RT   "Human keratinocytes that express hTERT and also bypass a
RT   p16(INK4a)-enforced mechanism that limits life span become immortal yet
RT   retain normal growth and differentiation characteristics.";
RL   Mol. Cell. Biol. 20:1436-1447(2000).
//
RX   PubMed=25169794; DOI=10.1111/jop.12236;
RA   Dickman C.T.D., Towle R., Saini R., Garnis C.;
RT   "Molecular characterization of immortalized normal and dysplastic oral
RT   cell lines.";
RL   J. Oral Pathol. Med. 44:329-336(2015).
//