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Cellosaurus PathHunter DLD1 MTNR1A Total GPCR Internalization (CVCL_KZ30)

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Cell line name PathHunter DLD1 MTNR1A Total GPCR Internalization
Synonyms PathHunter MTNR1A Total GPCR Internalization DLD1
Accession CVCL_KZ30
Resource Identification Initiative To cite this cell line use: PathHunter DLD1 MTNR1A Total GPCR Internalization (RRID:CVCL_KZ30)
Comments Population: Caucasian.
Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Transfected with: HGNC; 7463; MTNR1A.
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0248 (DLD-1)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Cross-references
Cell line collections (Providers) DiscoverX; 93-0847C13
Encyclopedic resources Wikidata; Q54938008
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number4