ID   PathHunter DLD1 MTNR1A Total GPCR Internalization
AC   CVCL_KZ30
SY   PathHunter MTNR1A Total GPCR Internalization DLD1
DR   DiscoverX; 93-0847C13
DR   Wikidata; Q54938008
CC   Population: Caucasian.
CC   Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
CC   Transfected with: HGNC; 7463; MTNR1A.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0248 ! DLD-1
SX   Male
AG   Adult
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 05-10-23; Version: 4
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