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Cellosaurus CellSensor Gli-bla 22Rv1 (CVCL_KS53)

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Cell line name CellSensor Gli-bla 22Rv1
Synonyms CellSensor Gli-bla 22Rv.1; Gli-bla 22Rv1; Gli-bla 22Rv.1
Accession CVCL_KS53
Resource Identification Initiative To cite this cell line use: CellSensor Gli-bla 22Rv1 (RRID:CVCL_KS53)
Comments Population: Caucasian.
Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of the Gli response element.
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P62593; Escherichia coli beta-lactamase bla (Note=With p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Leu597Arg (c.1790T>G); ClinVar=VCV000013968; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7133; KMT2D; Simple; p.Arg1252Ter (c.3754C>T); ClinVar=VCV000167228; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7133; KMT2D; Simple; p.Gln3158Ter (c.9472C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Gln546Arg (c.1637A>G); ClinVar=VCV000045466; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln331Arg (c.992A>G); ClinVar=VCV000421319; Zygosity=Heterozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1045 (22Rv1)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Web pages Provider; Thermo Fisher; K1838; https://www.thermofisher.com/order/catalog/product/K1838
Cross-references
Cell line databases/resources cancercelllines; CVCL_KS53
Encyclopedic resources Wikidata; Q54809181
Entry history
Entry creation22-Aug-2017
Last entry update14-Aug-2025
Version number16