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Cellosaurus CHO-AFLE (CVCL_JZ96)

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Cell line name CHO-AFLE
Accession CVCL_JZ96
Resource Identification Initiative To cite this cell line use: CHO-AFLE (RRID:CVCL_JZ96)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Korean Collection for Type Culture; KCTC 11015BP.
Characteristics: Transfected with a albumin-EPO fusion protein AFLE (Albumin-Full-Linker-EPO) (Patent=WO2008056961A1).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:399; ALB.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3415; EPO.
Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

Patent=WO2008056961A1
Sang-Lin Kim, Hyun-Kwang Tan, Sang-Min Lim, Jae-Kyoung Koo, Ju-Yeop Shin, Myung-Hwan Kim, Jong-Jin Lim, Chan-Hi Joung;
A novel fusion protein, cell lines expressing the same and preparation method thereof.
Patent number WO2008056961A1, 15-May-2008

Cross-references
Encyclopedic resources Wikidata; Q54812634
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number10