ID   CHO-AFLE
AC   CVCL_JZ96
DR   Wikidata; Q54812634
RX   Patent=WO2008056961A1;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Korean Collection for Type Culture; KCTC 11015BP.
CC   Characteristics: Transfected with a albumin-EPO fusion protein AFLE (Albumin-Full-Linker-EPO) (Patent=WO2008056961A1).
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:399; ALB.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3415; EPO.
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 22-08-17; Last updated: 19-12-24; Version: 10
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RX   Patent=WO2008056961A1;
RA   Kim S.-L., Tan H.-K., Lim S.-M., Koo J.-K., Shin J.-Y., Kim M.-H.,
RA   Lim J.-J., Joung C.-H.;
RT   "A novel fusion protein, cell lines expressing the same and
RT   preparation method thereof.";
RL   Patent number WO2008056961A1, 15-May-2008.
//