Cellosaurus cell line Kasumi-1 R48 (CVCL

Cellosaurus Kasumi-1 R48 (CVCL_JY44)

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Cell line name

Kasumi-1 R48

Synonyms

R48

Accession

CVCL_JY44

Resource Identification Initiative

To cite this cell line use: Kasumi-1 R48 (RRID:CVCL_JY44)

Comments

Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_49375; Dasatinib (BMS-354825).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Gene fusion; HGNC; HGNC:10471; RUNX1 + HGNC; HGNC:1535; RUNX1T1; Name(s)=RUNX1-RUNX1T1, AML1-ETO (from parent cell line).
Mutation; HGNC; HGNC:6342; KIT; Simple; p.Asn822Lys (c.2466T>A) (N818K); ClinVar=VCV000375931; Zygosity=Unspecified (from parent cell line).
Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Lys330Profs*6 (c.987insCCGG); Zygosity=Unspecified (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).

Disease

Childhood acute myeloid leukemia with maturation (NCIt: C9381)
Acute myeloblastic leukemia with maturation (ORDO: Orphanet_98834)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0589 (Kasumi-1)
Children:

CVCL_JY45 (Kasumi-1 PR48)

Sex of cell

Male

Age at sampling