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Cellosaurus PC12h (CVCL_JX88)

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Cell line name PC12h
Synonyms PC-12h; PC 12h; PC12 subclone h
Accession CVCL_JX88
Resource Identification Initiative To cite this cell line use: PC12h (RRID:CVCL_JX88)
Comments Characteristics: Shows NGF-mediated increase of tyrosine hydroxlyase activity.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Rat adrenal gland pheochromocytoma (NCIt: C121568)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS_0000603.
Hierarchy Parent: CVCL_0481 (PC12)
Children:
CVCL_JX89 (PC12h-R)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=6116517; DOI=10.1016/0006-8993(81)91029-5
Hiroshi Hatanaka;
Nerve growth factor-mediated stimulation of tyrosine hydroxylase activity in a clonal rat pheochromocytoma cell line.
Brain Res. 222:225-233(1981)

PubMed=6286607; DOI=10.1016/S0021-9258(18)34054-7
Nobuo Inoue, Hiroshi Hatanaka;
Nerve growth factor induces specific enkephalin binding sites in a nerve cell line.
J. Biol. Chem. 257:9238-9241(1982)

PubMed=2246260; DOI=10.1016/S0021-9258(17)45440-8
Kazuhiro Ikenaka, Kensuke Nakahira, Chitoshi Takayama, Kentaro Wada, Hiroshi Hatanaka, Katsuhiko Mikoshiba;
Nerve growth factor rapidly induces expression of the 68-kDa neurofilament gene by posttranscriptional modification in PC12h-R cells.
J. Biol. Chem. 265:19782-19785(1990)

PubMed=7530581; DOI=10.1016/0006-8993(94)91190-8
Masashi Yamada, Toshihiko Ikeuchi, Hiroko Tsukui, Saburo Aimoto, Hiroshi Hatanaka;
Sustained tyrosine phosphorylation of p140trkA in PC12h-R cells responding rapidly to NGF.
Brain Res. 661:137-146(1994)

Cross-references
Encyclopedic resources Wikidata; Q54938546
Experimental variables resources EFO; EFO_0022761
Entry history
Entry creation22-Aug-2017
Last entry update10-Apr-2025
Version number9