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Cellosaurus PC12h-R (CVCL_JX89)

[Text version]
Cell line name PC12h-R
Synonyms PC-12H-R; PC 12h-R
Accession CVCL_JX89
Resource Identification Initiative To cite this cell line use: PC12h-R (RRID:CVCL_JX89)
Comments Characteristics: Shows NGF-mediated increase of tyrosine hydroxlyase activity. Rapidly respond to NGF by extending its neurites without any delay.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Rat adrenal gland pheochromocytoma (NCIt: C121568)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS_0000603.
Hierarchy Parent: CVCL_JX88 (PC12h)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2246260; DOI=10.1016/S0021-9258(17)45440-8
Ikenaka K., Nakahira K., Takayama C., Wada K., Hatanaka H., Mikoshiba K.
Nerve growth factor rapidly induces expression of the 68-kDa neurofilament gene by posttranscriptional modification in PC12h-R cells.
J. Biol. Chem. 265:19782-19785(1990)

PubMed=7530581; DOI=10.1016/0006-8993(94)91190-8
Yamada M., Ikeuchi T., Tsukui H., Aimoto S., Hatanaka H.
Sustained tyrosine phosphorylation of p140trkA in PC12h-R cells responding rapidly to NGF.
Brain Res. 661:137-146(1994)

Cross-references
Encyclopedic resources Wikidata; Q54938547
Entry history
Entry creation22-Aug-2017
Last entry update10-Apr-2025
Version number9