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Cellosaurus KT-1/A3 (CVCL_JH29)

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Cell line name KT-1/A3
Synonyms A3
Accession CVCL_JH29
Resource Identification Initiative To cite this cell line use: KT-1/A3 (RRID:CVCL_JH29)
Comments Population: Japanese.
Characteristics: Interferon-alpha sensitive (PubMed=11111114).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D200 (KT-1 [Human leukemia])
Children:
CVCL_JH31 (KT-1/A3R)
Sex of cell Male
Age at sampling 32Y
Category Cancer cell line
Publications

PubMed=11111114; DOI=10.1159/000041061
Hayato Yamauchi, Ikuya Sakai, Hirosi Narumi, Shinji Soga, Shigeru Fujita;
Sensitivity to interferon-alpha and interferon-stimulated gene factor 3 binding activity in human chronic myelogenous leukemia cell line KT-1.
Acta Haematol. 104:1-9(2000)

PubMed=11506301; DOI=10.2169/internalmedicine.40.607
Hayato Yamauchi, Ikuya Sakai, Hirosi Narumi, Kazuto Takeuchi, Shinji Soga, Shigeru Fujita;
Development of interferon-alpha resistant subline from human chronic myelogenous leukemia cell line KT-1.
Intern. Med. 40:607-612(2001)

PubMed=12351404; DOI=10.1182/blood-2002-01-0073
Ikuya Sakai, Kazuto Takeuchi, Hayato Yamauchi, Hirosi Narumi, Shigeru Fujita;
Constitutive expression of SOCS3 confers resistance to IFN-alpha in chronic myelogenous leukemia cells.
Blood 100:2926-2931(2002)

Cross-references
Encyclopedic resources Wikidata; Q54900520
Entry history
Entry creation15-May-2017
Last entry update14-Aug-2025
Version number9