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Cellosaurus HB4a (CVCL_J982)

[Text version]
Cell line name HB4a
Synonyms Hb-4a; HB 4a
Accession CVCL_J982
Resource Identification Initiative To cite this cell line use: HB4a (RRID:CVCL_J982)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Deep proteome analysis.
Omics: Transcriptome analysis by massively parallel signature sequencing (MPSS).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Disease Breast carcinoma (NCIt: C4872)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_J983 (C3.6)CVCL_J984 (C5.2)
Sex of cell Female
Age at sampling 18Y
Category Conditionally immortalized cell line
Web pages https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/hb4a.htm

PubMed=8206680; DOI=10.1002/ijc.2910570616
Stamps A.C., Davies S.C., Burman J., O'Hare M.J.
Analysis of proviral integration in human mammary epithelial cell lines immortalized by retroviral infection with a temperature-sensitive SV40 T-antigen construct.
Int. J. Cancer 57:865-874(1994)

PubMed=11044355; DOI=10.1054/bjoc.2000.1458
Davidson J.M., Gorringe K.L., Chin S.-F., Orsetti B., Besret C., Courtay-Cahen C., Roberts I., Theillet C., Caldas C., Edwards P.A.W.
Molecular cytogenetic analysis of breast cancer cell lines.
Br. J. Cancer 83:1309-1317(2000)

PubMed=12671075; DOI=10.1073/pnas.0831040100
Jongeneel C.V., Iseli C., Stevenson B.J., Riggins G.J., Lal A., Mackay A., Harris R.A., O'Hare M.J., Neville A.M., Simpson A.J.G., Strausberg R.L.
Comprehensive sampling of gene expression in human cell lines with massively parallel signature sequencing.
Proc. Natl. Acad. Sci. U.S.A. 100:4702-4705(2003)

Silva A.P.M., Carraro D.M., Pires L.C., Jongeneel C.V., De Souza S.J., Camargo A.A.
Characterization of novel c-erbB2 regulated genes using massively parallel signature sequencing (MPSS).
Cancer Res. 66 Suppl. 8:19-20(2006)

PubMed=16685446; DOI=10.3892/ijo.28.6.1441
dos Santos M.L., Palanch C.G., Salaorni S., da Silva W.A. Jr., Nagai M.A.
Transcriptome characterization of human mammary cell lines expressing different levels of ERBB2 by serial analysis of gene expression.
Int. J. Oncol. 28:1441-1461(2006)

Anatomy/cell type resources BTO; BTO:0003893
Chemistry resources ChEMBL-Cells; CHEMBL3308647
ChEMBL-Targets; CHEMBL614786
PubChem_Cell_line; CVCL_J982
Encyclopedic resources Wikidata; Q54881361
Polymorphism and mutation databases Cosmic; 687470
Cosmic; 1609467
Proteomic databases PRIDE; PXD004195
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number16