Cellosaurus cell line t-HUE2 (CVCL

Cellosaurus t-HUE2 (CVCL_J427)

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Cell line name

t-HUE2

Accession

CVCL_J427

Resource Identification Initiative

To cite this cell line use: t-HUE2 (RRID:CVCL_J427)

Comments

Group: Serum/protein free medium cell line.
Problematic cell line: Contaminated. Parent cell line (ECV-304) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Doubling time: 35 hours (PubMed=1817644).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.

Sequence variations

Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).

Disease

Bladder carcinoma (NCIt: C4912)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_2029 (ECV-304)
Children:

CVCL_J428 (t-HUE4)

Sex of cell

Female

Age at sampling

82Y