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Cellosaurus t-HUE4 (CVCL_J428)

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Cell line name t-HUE4
Accession CVCL_J428
Resource Identification Initiative To cite this cell line use: t-HUE4 (RRID:CVCL_J428)
Comments Group: Serum/protein free medium cell line.
Problematic cell line: Contaminated. Grand-parent cell line (ECV-304) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Doubling time: 45 hours (PubMed=1817644).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_J427 (t-HUE2)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=1817644
Mieko Kobayashi, Masaaki Kondo, Youji Mitsui;
Establishment of human endothelial cell lines in a serum-free culture and its application for expression of transfected prepro endothelin gene.
Hum. Cell 4:296-305(1991)

Cross-references
Cell line databases/resources cancercelllines; CVCL_J428
Encyclopedic resources Wikidata; Q54971366
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number17