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Cellosaurus hPheo1 (CVCL_IY88)

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Cell line name hPheo1
Accession CVCL_IY88
Resource Identification Initiative To cite this cell line use: hPheo1 (RRID:CVCL_IY88)
Comments Doubling time: ~1.2 days (PubMed=23785438).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Adrenal gland pheochromocytoma (NCIt: C3326)
Sporadic pheochromocytoma/secreting paraganglioma (ORDO: Orphanet_276621)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C6JR (hPheo1 KD-SDHB)
Sex of cell Female
Age at sampling 39Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=23785438

Markers:
AmelogeninX
CSF1PO11,12
D5S81812,13
D7S8208,12
D13S3178,12
D16S53911,13
TH016,7
TPOX8
vWA16

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Publications

PubMed=23785438; DOI=10.1371/journal.pone.0065624; PMCID=PMC3681983
Hans K. Ghayee, Vikash J. Bhagwandin, Victor A. Stastny, Arielle Click, Liang-Hao Ding, Dario Mizrachi, Ying S. Zou, Raj Chari, Wan L. Lam, Robert M. Bachoo, Alice L. Smith ...Show all 18 authors... , Michael D. Story, Stan Sidhu, Bruce G. Robinson, Fiemu E. Nwariaku, Adi F. Gazdar, Richard J. Auchus, Jerry W. Shay; Show fewer authors
Progenitor cell line (hPheo1) derived from a human pheochromocytoma tumor.
PLoS ONE 8:e65624.1-e65624.8(2013)

PubMed=35008989; DOI=10.3390/ijms23010560; PMCID=PMC8745660
Mouna Tabebi, Ravi Kumar Dutta, Camilla Skoglund, Peter Soderkvist, Oliver Gimm;
Loss of SDHB induces a metabolic switch in the hPheo1 cell line toward enhanced OXPHOS.
Int. J. Mol. Sci. 23:560.1-560.18(2022)

Cross-references
Encyclopedic resources Wikidata; Q54890291
Entry history
Entry creation15-May-2017
Last entry update14-Aug-2025
Version number12