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Cellosaurus hPheo1 (CVCL_IY88)

[Text version]
Cell line name hPheo1
Accession CVCL_IY88
Resource Identification Initiative To cite this cell line use: hPheo1 (RRID:CVCL_IY88)
Comments Doubling time: ~1.2 days (PubMed=23785438).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Adrenal gland pheochromocytoma (NCIt: C3326)
Sporadic pheochromocytoma/secreting paraganglioma (ORDO: Orphanet_276621)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C6JR (hPheo1 KD-SDHB)
Sex of cell Female
Age at sampling 39Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=23785438

Markers:
AmelogeninX
CSF1PO11,12
D5S81812,13
D7S8208,12
D13S3178,12
D16S53911,13
TH016,7
TPOX8
vWA16

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Publications

PubMed=23785438; DOI=10.1371/journal.pone.0065624; PMCID=PMC3681983
Ghayee H.K., Bhagwandin V.J., Stastny V.A., Click A., Ding L.-H., Mizrachi D., Zou Y.S., Chari R., Lam W.L., Bachoo R.M., Smith A.L., Story M.D., Sidhu S., Robinson B.G., Nwariaku F.E., Gazdar A.F., Auchus R.J., Shay J.W.
Progenitor cell line (hPheo1) derived from a human pheochromocytoma tumor.
PLoS ONE 8:e65624.1-e65624.8(2013)

PubMed=35008989; DOI=10.3390/ijms23010560; PMCID=PMC8745660
Tabebi M., Kumar Dutta R., Skoglund C., Soderkvist P., Gimm O.
Loss of SDHB induces a metabolic switch in the hPheo1 cell line toward enhanced OXPHOS.
Int. J. Mol. Sci. 23:560.1-560.18(2022)

Cross-references
Encyclopedic resources Wikidata; Q54890291
Entry history
Entry creation15-May-2017
Last entry update10-Apr-2025
Version number11