ID   hPheo1
AC   CVCL_IY88
DR   Wikidata; Q54890291
RX   PubMed=23785438;
RX   PubMed=35008989;
CC   Doubling time: ~1.2 days (PubMed=23785438).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
ST   Source(s): PubMed=23785438
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 8,12
ST   D16S539: 11,13
ST   D5S818: 12,13
ST   D7S820: 8,12
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 16
DI   NCIt; C3326; Adrenal gland pheochromocytoma
DI   ORDO; Orphanet_276621; Sporadic pheochromocytoma/secreting paraganglioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   39Y
CA   Telomerase immortalized cell line
DT   Created: 15-05-17; Last updated: 10-04-25; Version: 11
//
RX   PubMed=23785438; DOI=10.1371/journal.pone.0065624; PMCID=PMC3681983;
RA   Ghayee H.K., Bhagwandin V.J., Stastny V.A., Click A., Ding L.-H.,
RA   Mizrachi D., Zou Y.S., Chari R., Lam W.L., Bachoo R.M., Smith A.L.,
RA   Story M.D., Sidhu S., Robinson B.G., Nwariaku F.E., Gazdar A.F.,
RA   Auchus R.J., Shay J.W.;
RT   "Progenitor cell line (hPheo1) derived from a human pheochromocytoma
RT   tumor.";
RL   PLoS ONE 8:e65624.1-e65624.8(2013).
//
RX   PubMed=35008989; DOI=10.3390/ijms23010560; PMCID=PMC8745660;
RA   Tabebi M., Kumar Dutta R., Skoglund C., Soderkvist P., Gimm O.;
RT   "Loss of SDHB induces a metabolic switch in the hPheo1 cell line
RT   toward enhanced OXPHOS.";
RL   Int. J. Mol. Sci. 23:560.1-560.18(2022).
//