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Cellosaurus hPheo1 KD-SDHB (CVCL_C6JR)

[Text version]
Cell line name hPheo1 KD-SDHB
Synonyms KD-SDHB hPheo1
Accession CVCL_C6JR
Resource Identification Initiative To cite this cell line use: hPheo1 KD-SDHB (RRID:CVCL_C6JR)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10681; SDHB (Note=1 of 2 alleles).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Adrenal gland pheochromocytoma (NCIt: C3326)
Sporadic pheochromocytoma/secreting paraganglioma (ORDO: Orphanet_276621)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IY88 (hPheo1)
Sex of cell Female
Age at sampling 39Y
Category Telomerase immortalized cell line
Publications

PubMed=35008989; DOI=10.3390/ijms23010560; PMCID=PMC8745660
Tabebi M., Kumar Dutta R., Skoglund C., Soderkvist P., Gimm O.
Loss of SDHB induces a metabolic switch in the hPheo1 cell line toward enhanced OXPHOS.
Int. J. Mol. Sci. 23:560.1-560.18(2022)

Cross-references
Encyclopedic resources Wikidata; Q116049333
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number6