ID   hPheo1 KD-SDHB
AC   CVCL_C6JR
SY   KD-SDHB hPheo1
DR   Wikidata; Q116049333
RX   PubMed=35008989;
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10681; SDHB (Note=1 of 2 alleles).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
DI   NCIt; C3326; Adrenal gland pheochromocytoma
DI   ORDO; Orphanet_276621; Sporadic pheochromocytoma/secreting paraganglioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_IY88 ! hPheo1
SX   Female
AG   39Y
CA   Telomerase immortalized cell line
DT   Created: 15-12-22; Last updated: 19-12-24; Version: 6
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RX   PubMed=35008989; DOI=10.3390/ijms23010560; PMCID=PMC8745660;
RA   Tabebi M., Kumar Dutta R., Skoglund C., Soderkvist P., Gimm O.;
RT   "Loss of SDHB induces a metabolic switch in the hPheo1 cell line
RT   toward enhanced OXPHOS.";
RL   Int. J. Mol. Sci. 23:560.1-560.18(2022).
//