Cellosaurus cell line ID8-Luc2 (CVCL

Cellosaurus ID8-Luc2 (CVCL_IU16)

Cross-references
Cell line name	ID8-Luc2
Synonyms	ID8luc2
Accession	CVCL_IU16
Resource Identification Initiative	To cite this cell line use: ID8-Luc2 (RRID:CVCL_IU16)
Comments	Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304. Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6.
Hierarchy	Parent: CVCL_IU14 (ID8)
Sex of cell	Female
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=25992288; DOI=10.1186/s40425-015-0060-6; PMCID=PMC4437454 John B. Liao, Kelsie J. Ovenell, Erin E.M. Curtis, Denise L. Cecil, Marlese R. Koehnlein, Lauren R. Rastetter, Ekram A. Gad, Mary L. Disis; Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer. J. Immunother. Cancer 3:16.1-16.9(2015) PubMed=26676113; DOI=10.1186/s40425-015-0102-0; PMCID=PMC4678634 Thais Baert, Tina Verschuere, Anais Van Hoylandt, Rik Gijsbers, Ignace Vergote, An Coosemans; The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer. J. Immunother. Cancer 3:57.1-57.5(2015) PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028; PMCID=PMC4961516 Lidia Hernandez, Marianne K. Kim, L. Tiffany Lyle, Kristen P. Bunch, Carrie D. House, Franklin Ning, Anne M. Noonan, Christina Messineo Annunziata; Characterization of ovarian cancer cell lines as in vivo models for preclinical studies. Gynecol. Oncol. 142:332-340(2016)
Encyclopedic resources	Wikidata; Q54897295
Entry history
Entry creation	03-Mar-2017
Last entry update	14-Aug-2025
Version number	9