ID   ID8-Luc2
AC   CVCL_IU16
SY   ID8luc2
DR   Wikidata; Q54897295
RX   PubMed=25992288;
RX   PubMed=26676113;
RX   PubMed=27235858;
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_IU14 ! ID8
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 03-03-17; Last updated: 10-04-25; Version: 8
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RX   PubMed=25992288; DOI=10.1186/s40425-015-0060-6; PMCID=PMC4437454;
RA   Liao J.B., Ovenell K.J., Curtis E.E.M., Cecil D.L., Koehnlein M.R.,
RA   Rastetter L.R., Gad E.A., Disis M.L.;
RT   "Preservation of tumor-host immune interactions with luciferase-tagged
RT   imaging in a murine model of ovarian cancer.";
RL   J. Immunother. Cancer 3:16.1-16.9(2015).
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RX   PubMed=26676113; DOI=10.1186/s40425-015-0102-0; PMCID=PMC4678634;
RA   Baert T., Verschuere T., Van Hoylandt A., Gijsbers R., Vergote I.,
RA   Coosemans A.;
RT   "The dark side of ID8-Luc2: pitfalls for luciferase tagged murine
RT   models for ovarian cancer.";
RL   J. Immunother. Cancer 3:57.1-57.5(2015).
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RX   PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028; PMCID=PMC4961516;
RA   Hernandez L., Kim M.K., Lyle L.T., Bunch K.P., House C.D., Ning F.,
RA   Noonan A.M., Annunziata C.M.;
RT   "Characterization of ovarian cancer cell lines as in vivo models for
RT   preclinical studies.";
RL   Gynecol. Oncol. 142:332-340(2016).
//