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Cellosaurus ID8 (CVCL_IU14)

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Cell line name ID8
Synonyms ID8/MOSEC
Accession CVCL_IU14
Resource Identification Initiative To cite this cell line use: ID8 (RRID:CVCL_IU14)
Comments Characteristics: Physiologically and biologically closely resembles human epithelial ovarian cancer.
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_F1K9 (ID8 Brca1 KO)CVCL_E6ZE (ID8 fat-1)CVCL_F1KA (ID8 Trp53 KO)
CVCL_VA22 (ID8-B7H6)CVCL_IU15 (ID8-Fluc)CVCL_C8UV (ID8-Luc)
CVCL_IU16 (ID8-Luc2)CVCL_E0W3 (Ubigene ID8 Arid1a KO)CVCL_E0W4 (Ubigene ID8 Atrx KO)
CVCL_E0W5 (Ubigene ID8 Fat1 KO)CVCL_E0W6 (Ubigene ID8 Hk2 KO)CVCL_E0W7 (Ubigene ID8 Kmt2c KO)
CVCL_E0W8 (Ubigene ID8 Kmt2d KO)CVCL_E0W9 (Ubigene ID8 Rb1 KO)CVCL_E0WA (Ubigene ID8 Smarca4 KO)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
STR profile Source(s): Millipore=SCC145; Ubigene=YC-C103

Markers:
Mouse STR 1-116
Mouse STR 1-220
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-219.3
Mouse STR 5-517
Mouse STR 6-418
Mouse STR 6-715
Mouse STR 7-126.2
Mouse STR 8-118
Mouse STR 11-216
Mouse STR 12-117
Mouse STR 13-117
Mouse STR 15-322.3
Mouse STR 17-215
Mouse STR 18-317
Mouse STR 19-213
Mouse STR X-127

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Publications

PubMed=10753190; DOI=10.1093/carcin/21.4.585
Katherine F. Roby, Christopher C. Taylor, Jeffrey P. Sweetwood, Ying Cheng, Judith L. Pace, Ossama Tawfik, Diane L. Persons, Peter G. Smith, Paul F. Terranova;
Development of a syngeneic mouse model for events related to ovarian cancer.
Carcinogenesis 21:585-591(2000)

PubMed=16886597
Margit Maria Janat-Amsbury, James William Yockman, Matthew Linley Anderson, Dirk Gunter Kieback, Sung Wan Kim;
Comparison of ID8 MOSE and VEGF-modified ID8 cell lines in an immunocompetent animal model for human ovarian cancer.
Anticancer Res. 26:2785-2789(2006)

PubMed=18036641; DOI=10.1016/j.ygyno.2007.10.035
James Greenaway, Roger Moorehead, Patricia Shaw, Jim Petrik;
Epithelial-stromal interaction increases cell proliferation, survival and tumorigenicity in a mouse model of human epithelial ovarian cancer.
Gynecol. Oncol. 108:385-394(2008)

PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028; PMCID=PMC4961516
Lidia Hernandez, Marianne K. Kim, L. Tiffany Lyle, Kristen Paige Bunch, Carrie D. House, Franklin Ning, Anne M. Noonan, Christina Messineo Annunziata;
Characterization of ovarian cancer cell lines as in vivo models for preclinical studies.
Gynecol. Oncol. 142:332-340(2016)

Cross-references
Cell line collections (Providers) CLS; 305305
Millipore; SCC145
Ubigene; YC-C103
Encyclopedic resources Wikidata; Q54897292
Proteomic databases PRIDE; PXD013062
Entry history
Entry creation03-Mar-2017
Last entry update10-Apr-2025
Version number11