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Cellosaurus CHO-13D-35D (CVCL_IR13)

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Cell line name CHO-13D-35D
Synonyms CHO 13D-35D; 13D-35D
Accession CVCL_IR13
Resource Identification Initiative To cite this cell line use: CHO-13D-35D (RRID:CVCL_IR13)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:775; SERPINC1.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=18078289; DOI=10.1002/bit.21758
Tomoshi Ohya, Tetsuji Hayashi, Eriko Kiyama, Hiroko Nishii, Hideo Miki, Kaoru Kobayashi, Kohsuke Honda, Takeshi Omasa, Hisao Ohtake;
Improved production of recombinant human antithrombin III in Chinese hamster ovary cells by ATF4 overexpression.
Biotechnol. Bioeng. 100:317-324(2008)

PubMed=19134553; DOI=10.1263/jbb.106.568
Takeshi Omasa, Takashi Takami, Tomoshi Ohya, Eriko Kiyama, Tetsuji Hayashi, Hiroko Nishii, Hideo Miki, Kaoru Kobayashi, Kohsuke Honda, Hisao Ohtake;
Overexpression of GADD34 enhances production of recombinant human antithrombin III in Chinese hamster ovary cells.
J. Biosci. Bioeng. 106:568-573(2008)

Cross-references
Encyclopedic resources Wikidata; Q54812612
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number9