ID   CHO-13D-35D
AC   CVCL_IR13
SY   CHO 13D-35D; 13D-35D
DR   Wikidata; Q54812612
RX   PubMed=18078289;
RX   PubMed=19134553;
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:775; SERPINC1.
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 03-03-17; Last updated: 19-12-24; Version: 9
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RX   PubMed=18078289; DOI=10.1002/bit.21758;
RA   Ohya T., Hayashi T., Kiyama E., Nishii H., Miki H., Kobayashi K.,
RA   Honda K., Omasa T., Ohtake H.;
RT   "Improved production of recombinant human antithrombin III in Chinese
RT   hamster ovary cells by ATF4 overexpression.";
RL   Biotechnol. Bioeng. 100:317-324(2008).
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RX   PubMed=19134553; DOI=10.1263/jbb.106.568;
RA   Omasa T., Takami T., Ohya T., Kiyama E., Hayashi T., Nishii H.,
RA   Miki H., Kobayashi K., Honda K., Ohtake H.;
RT   "Overexpression of GADD34 enhances production of recombinant human
RT   antithrombin III in Chinese hamster ovary cells.";
RL   J. Biosci. Bioeng. 106:568-573(2008).
//