Cellosaurus cell line 6CFSMEo- (CVCL

Cellosaurus 6CFSMEo- (CVCL_IN62)

[Text version]

Cell line name

6CFSMEo-

Synonyms

6CFSMEO

Accession

CVCL_IN62

Resource Identification Initiative

To cite this cell line use: 6CFSMEo- (RRID:CVCL_IN62)

Comments

Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Lung, bronchus, submucosal gland; UBERON=UBERON_8410043.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.

Sequence variations

Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Gln2Ter (c.4C>T); ClinVar=VCV000053980; Zygosity=Heterozygous (PubMed=15463957; PubMed=16037690).
Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (PubMed=15463957; PubMed=16037690).

Disease

Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_VP33 ! CFSMEo-
CVCL_IN60 ! 2CFSMEo-
CVCL_IN58 ! 3ACFSMEo-

Sex of cell

Sex unspecified

Age at sampling

Age unspecified

Category

Transformed cell line

STR profile

Source(s): Millipore=SCC157

Markers:

Amelogenin	X
CSF1PO	9,12
D3S1358	15,18
D5S818	11,12
D7S820	9
D8S1179	8,13
D13S317	12
D16S539	14
D18S51	16,20
D21S11	29,30
FGA	19
Penta D	9,10
Penta E	10,11
TH01	7,9.3
TPOX	8,11
vWA	14,17

Publications

PubMed=1375758; DOI=10.1073/pnas.89.11.5171; PMCID=PMC49251
Alison L. Cozens, Michael J. Yezzi, Lynda Chin, E.M. Simon, Walter E. Finkbeiner, John A. Wagner, Dieter C. Gruenert;
Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells.
Proc. Natl. Acad. Sci. U.S.A. 89:5171-5175(1992)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Dieter C. Gruenert, Marjolaine Willems, Jean-Jacques Cassiman, Raymond A. Frizzell;
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

PubMed=16037690; DOI=10.1159/000087235
Ana Carina da Paula, Anabela Santo Ramalho, Carlos M. Farinha, Judy Cheung, Rosalie Maurisse, Dieter C. Gruenert, Jiraporn Ousingsawat, Karl Kunzelmann, Margarida Duarte Amaral;
Characterization of novel airway submucosal gland cell models for cystic fibrosis studies.
Cell. Physiol. Biochem. 15:251-262(2005)

Cross-references

Cell line collections (Providers)

Millipore; SCC157

Encyclopedic resources

Wikidata; Q54604526

Entry history

Entry creation

01-Dec-2016

Last entry update

19-Dec-2024

Version number